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Titolo:
New strategies in the treatment of graft-versus-host disease
Autore:
Basara, N; Blau, IW; Willenbacher, W; Kiehl, MG; Fauser, AA;
Indirizzi:
Clin Bone Marrow Transplantat & Hematol Oncol, D-55743 Idar Oberstein, Germany Clin Bone Marrow Transplantat & Hematol Oncol Idar Oberstein GermanyD-55743
Titolo Testata:
BONE MARROW TRANSPLANTATION
, volume: 25, anno: 2000, supplemento:, 2
pagine: S12 - S15
SICI:
0268-3369(200005)25:<S12:NSITTO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW TRANSPLANTATION; MYCOPHENOLATE-MOFETIL; CHRONIC GVHD; METHOTREXATE; PROPHYLAXIS; THALIDOMIDE; DONORS;
Keywords:
mycophenolate mofetil; GVHD; hemopoietic stem cell transplantation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Basara, N Clin Bone Marrow Transplantat & Hematol Oncol, Dr Ottmar Kohler Str 2, D-55743 Idar Oberstein, Germany Clin Bone Marrow Transplantat & Hematol Oncol Dr Ottmar Kohler Str 2 Idar Oberstein Germany D-55743
Citazione:
N. Basara et al., "New strategies in the treatment of graft-versus-host disease", BONE MAR TR, 25, 2000, pp. S12-S15

Abstract

GVHD continues to be a major complication after allogeneic hematopoietic stem cell transplantation even when the recipient is given immunosuppressionfor the prophylaxis of this severe disease. There have been many advances in the prevention and treatment of GVHD, using compounds such as cyclosporine, FK506, mycophenolate mofetil or monoclonal IL-2 receptor antagonist. New strategies seem to include sequential therapy involving the blocking of both endogenous cytokines and alloreactive donor cells. However, further clinical and laboratory studies are needed in order to improve the therapy of established GVHD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 00:10:50