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Titolo:
Fast echo planar based correlation-peak imaging: Demonstration on the rat brain in vivo
Autore:
Mayer, D; Dreher, W; Leibfritz, D;
Indirizzi:
Univ Bremen, Fachbereich Chem 2, D-28334 Bremen, Germany Univ Bremen Bremen Germany D-28334 reich Chem 2, D-28334 Bremen, Germany
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 1, volume: 44, anno: 2000,
pagine: 23 - 28
SICI:
0740-3194(200007)44:1<23:FEPBCI>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEAR-MAGNETIC-RESONANCE; PULSED FIELD GRADIENTS; TWO-DIMENSIONAL NMR; CHEMICAL-SHIFT; COSY SPECTRA; IN-VIVO; SPECTROSCOPY; TIME; METABOLITES; SENSITIVITY;
Keywords:
proton spectroscopic imaging; echo planar encoding; correlation spectroscopy; rat brain;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Leibfritz, D Univ Bremen, Fachbereich Chem 2, Leobener Str, D-28334 Bremen, Germany Univ Bremen Leobener Str Bremen Germany D-28334 men, Germany
Citazione:
D. Mayer et al., "Fast echo planar based correlation-peak imaging: Demonstration on the rat brain in vivo", MAGN RES M, 44(1), 2000, pp. 23-28

Abstract

Two-dimensional correlation spectroscopy (2D-COSY) was combined with a fast echo planar based spectroscopic imaging technique in a new sequence. It can be optimized according to the coupling patterns of particular metabolites by using a constant time (CT) variant of COSY with chemical shift selective excitation and refocusing. Experiments were performed with an evolution time of 110 ms which was determined by simulating the CT-COSY experiment atseveral evolution times for the spin systems of myo-inositol (Ins) and taurine (Tau). The sequence has a minimum total measurement time of 17 min andwas tested on a spherical phantom filled with a solution of Ins. The in vivo application of this method on the healthy rat brain demonstrates its improved spectral resolution as cross-peak signals from both Ins and Tau can be separated clearly. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 08:11:36