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Titolo:
ANALYSIS OF INBREEDING IN A COLONIZING POPULATION OF DROSOPHILA-SUBOBSCURA
Autore:
PEGUEROLES G; MESTRES F; SERRA L;
Indirizzi:
UNIV BARCELONA,FAC BIOL,DEPT GENET,AV DIAGONAL 645 E-08071 BARCELONA SPAIN UNIV BARCELONA,FAC BIOL,DEPT GENET E-08071 BARCELONA SPAIN
Titolo Testata:
Genetica
fascicolo: 3, volume: 98, anno: 1996,
pagine: 289 - 296
SICI:
0016-6707(1996)98:3<289:AOIIAC>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHROMOSOMAL ARRANGEMENTS; COLONIZATION; AMERICA; MELANOGASTER; POLYMORPHISM; ASSOCIATION; DEPRESSION; INVERSION; PATTERNS; CLINES;
Keywords:
DROSOPHILA SUBOBSCURA; FIXATION RATES; SIB MATING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
G. Pegueroles et al., "ANALYSIS OF INBREEDING IN A COLONIZING POPULATION OF DROSOPHILA-SUBOBSCURA", Genetica, 98(3), 1996, pp. 289-296

Abstract

An analysis of the effects of inbreeding on the genetic structure of a colonizing population of Drosophila subobscura has been carried out. Species of Drosophila, particularly D. subobscura, may have lethal alleles associated with chromosomal inversions and our aim was to assessthe extent to which the genome is balanced in this way. The frequencies of chromosomal inversions were compared between a large population and a set of 72 lines that were maintained by brother-Sister mating for 10 generations. Fisher's matrix method was used to calculate the expected homozygosity in these inbred lines for 5 allozyme loci (Aph, Hk-1, Lap, Odh, and Pept-1) used as markers of large chromosomal segments. Furthermore, the expected rates of fixation corresponding to these allozyme loci were also calculated. The results show that the amount ofhomozygosis observed did not differ significantly from expectations (with the corresponding loss of lines as a consequence of the reductionin viability). However, two deviations from strict neutrality were observed: there was a heterozygote excess at the Lap locus, and the frequency of the O-5 inversion (always associated with a lethal gene in colonizing populations) was higher than expected.

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Documento generato il 03/12/20 alle ore 21:38:08