Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Cartilage formation by cultured chondrocytes in a new scaffold made of poly(L-lactide-epsilon-caprolactone) sponge
Autore:
Honda, M; Yada, T; Ueda, M; Kimata, K;
Indirizzi:
Nagoya Univ, Sch Med, Dept Oral Surg, Showa Ku, Nagoya, Aichi 4668550, Japan Nagoya Univ Nagoya Aichi Japan 4668550 a Ku, Nagoya, Aichi 4668550, Japan Aichi Med Univ, Inst Mol Sci Med, Aichi, Japan Aichi Med Univ Aichi Japan chi Med Univ, Inst Mol Sci Med, Aichi, Japan
Titolo Testata:
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
fascicolo: 7, volume: 58, anno: 2000,
pagine: 767 - 775
SICI:
0278-2391(200007)58:7<767:CFBCCI>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
BIODEGRADABLE POLYMERS; ALLOGRAFT CHONDROCYTES; ARTICULAR SURFACES; GROWTH; POLY(EPSILON-CAPROLACTONE); REGENERATION; DEGRADATION; COPOLYMERS; FIXATION; INVITRO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Honda, M Nagoya Univ, Sch Med, Dept Oral Surg, Showa Ku, 65 Tsuruma Cho, Nagoya, Aichi 4668550, Japan Nagoya Univ 65 Tsuruma Cho Nagoya Aichi Japan 4668550 8550, Japan
Citazione:
M. Honda et al., "Cartilage formation by cultured chondrocytes in a new scaffold made of poly(L-lactide-epsilon-caprolactone) sponge", J ORAL MAX, 58(7), 2000, pp. 767-775

Abstract

Purpose: This study investigated the ability of chondrocytes grown in culture and inoculated into a newly developed biodegradable sponge to form ectopic cartilage tissue. Materials and Methods: Chondrocytes obtained from costochondral cartilage dissected from Lewis rats were cultured to allow proliferation and then were inoculated into a sponge consisting of a biodegradable polymer, poly (L-lactide-epsilon-caprolactone). The composites of chondrocytes and sponge were transplanted subcutaneously into Nude mice and removed after 4 weeks for histologic and Northern blot analysis. Results: Staining with hematoxylin and eosin showed the formation of a cartilage-like structure in the sponge. Northern blot analysis of the total RNA in the composites showed the presence of aggrecan transcripts of about 9 kb. Conclusion: The poly (L-lactide-epsilon-caprolactone) sponge system, is suitable as a matrix for tissue-engineered cartilage. (C) 2000 American Association of Oral and Maxillofacial Surgeons.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/06/20 alle ore 01:37:28