Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Synaptic interactions between thalamic inputs to simple cells in cat visual cortex
Autore:
Usrey, WM; Alonso, JM; Reid, RC;
Indirizzi:
Harvard Univ, Sch Med, Dept Neurobiol, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 ed, Dept Neurobiol, Boston, MA 02115 USA Rockefeller Univ, Neurobiol Lab, New York, NY 10021 USA Rockefeller Univ New York NY USA 10021 robiol Lab, New York, NY 10021 USA Univ Connecticut, Dept Psychol, Storrs, CT 06269 USA Univ Connecticut Storrs CT USA 06269 , Dept Psychol, Storrs, CT 06269 USA
Titolo Testata:
JOURNAL OF NEUROSCIENCE
fascicolo: 14, volume: 20, anno: 2000,
pagine: 5461 - 5467
SICI:
0270-6474(20000715)20:14<5461:SIBTIT>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEOCORTICAL PYRAMIDAL NEURONS; LATERAL GENICULATE-NUCLEUS; RECEPTIVE-FIELD PROPERTIES; CALCIUM ACTION-POTENTIALS; SHORT-TERM PLASTICITY; STRIATE CORTEX; HIPPOCAMPAL SYNAPSES; RETINAL INPUTS; EFFICACY; INFORMATION;
Keywords:
lateral geniculate nucleus; thalamus; area 17; geniculocortical; coincidence detection;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Reid, RC Harvard Univ, Sch Med, Dept Neurobiol, 220 Longwood Ave, Boston, MA 02115 USA Harvard Univ 220 Longwood Ave Boston MA USA 02115 n, MA 02115 USA
Citazione:
W.M. Usrey et al., "Synaptic interactions between thalamic inputs to simple cells in cat visual cortex", J NEUROSC, 20(14), 2000, pp. 5461-5467

Abstract

We performed experiments in the cat geniculocortical pathway, in vivo, to examine how presynaptic spikes interact to influence the firing of postsynaptic targets. In particular, we asked (1) how do multiple spikes from a single presynaptic neuron interact to influence the firing of a postsynaptic target (homosynaptic interactions), (2) how do spikes from two different presynaptic neurons interact (heterosynaptic interactions), and (3) what is the time course of homosynaptic and heterosynaptic interactions? We found that both homosynaptic and heterosynaptic interactions increase the likelihoodof driving a postsynaptic spike, although with different time courses. Fortwo spikes traveling down a single geniculate axon, the second spike is more effective than the first for similar to 15 msec. For two spikes on separate axons, the interaction is faster (similar to 7 msec duration, similar to 2.5 msec time constant). Thus changes in firing rate are perhaps best relayed by homosynaptic interactions, whereas heterosynaptic interactions may help detect coincident spikes from different thalamic inputs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 06:22:19