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Titolo:
MANAGEMENT OF NODULAR DIFFERENTIATED THYR OID-CANCER
Autore:
VISSET J; MIRALLIE E; HAMY A; PAINEAU J; SAGAN C;
Indirizzi:
HOP LAENNEC,CLIN CHIRURG 1 F-44035 NANTES 01 FRANCE
Titolo Testata:
Annales d'Endocrinologie
fascicolo: 3, volume: 58, anno: 1997,
pagine: 216 - 224
SICI:
0003-4266(1997)58:3<216:MONDTO>2.0.ZU;2-#
Fonte:
ISI
Lingua:
FRE
Soggetto:
PROGNOSTIC SCORING SYSTEM; LYMPH-NODE METASTASES; COMPLETION THYROIDECTOMY; RETROSPECTIVE ANALYSIS; SURGICAL-MANAGEMENT; CARCINOMA; PAPILLARY; MULTIVARIATE; LOBECTOMY; MORTALITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
56
Recensione:
Indirizzi per estratti:
Citazione:
J. Visset et al., "MANAGEMENT OF NODULAR DIFFERENTIATED THYR OID-CANCER", Annales d'Endocrinologie, 58(3), 1997, pp. 216-224

Abstract

Mortality and recurrence rate in nodular forms of differentiated thyroid cancer are 10 and 15%, raising the question of whether initial treatment was adequate. Recurrence and mortality appear to be higher after lobectomy than after total thyroidectomy. This could result from thedevelopment of dediferentiated relapse or metastasis from residual areas. Metastatic node invasion is frequent (60 to 80%) but does not lead to a high recurrence rate. Prognosis is poor however due to frequentassociation with visceral metastases. Management should take into account the relative degree of malignancy of this cancer and the risk of mobidity for long surgical procedures. Lobectomy can be acceptable if no criteria of gravity is observed, but total thyroidectomy remains the treatment of choice. In patients with criteria of gravity, needle biopsy guides possible node dissection. Dissection of the recurrent chain misses 20% at the metastatic nodes, while dissection of the supraclavian and middle jugular recurrent chains only misses 7.8%. Radioactiveiodine and homone therapy are also indicated in patients with signs of gravity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 06:21:47