Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
HANDLING STRESS DOES NOT AFFECT THE EXPRESSION OF HEPATIC HEAT-SHOCK-PROTEIN-70 AND CONJUGATION ENZYMES IN RAINBOW-TROUT TREATED WITH BETA-NAPHTHOFLAVONE
Autore:
VIJAYAN MM; PEREIRA C; FORSYTH RB; KENNEDY CJ; IWAMA GK;
Indirizzi:
UNIV BRITISH COLUMBIA,DEPT ANIM SCI,208-2357 MAIN MALL VANCOUVER BC V6T 1Z4 CANADA BIOSTRESS RES VANCOUVER BC CANADA SIMON FRASER UNIV,DEPT BIOL SCI BURNABY BC V5A 1S6 CANADA
Titolo Testata:
Life sciences
fascicolo: 2, volume: 61, anno: 1997,
pagine: 117 - 127
SICI:
0024-3205(1997)61:2<117:HSDNAT>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
METABOLISM; INDUCTION; TOXICITY; FISH; HEPATOCYTES; ANTIBODIES; ASSAY; LIVER;
Keywords:
TROUT; ONCORHYNCHUS MYKISS; HEAT SHOCK PROTEIN 70; ETHOXYRESORUFIN O-DEETHYLASE; URIDINE-5'-DIPHOSPHOGLUCURONIC ACID TRANSFERASE; GLUCONEOGENESIS; INTERMEDIARY METABOLISM; STRESS; CORTISOL; GLUCOSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
M.M. Vijayan et al., "HANDLING STRESS DOES NOT AFFECT THE EXPRESSION OF HEPATIC HEAT-SHOCK-PROTEIN-70 AND CONJUGATION ENZYMES IN RAINBOW-TROUT TREATED WITH BETA-NAPHTHOFLAVONE", Life sciences, 61(2), 1997, pp. 117-127

Abstract

A response in heat shock protein 70 (hsp 70) expression in the a-naphthoflavone (BNF) treated rainbow trout (Oncorhynchus mykiss) corresponded to altered metabolic status of the liver as evidenced by the lowerphosphoenolpyruvate carboxykinase (PEPCK), lactate dehydrogenase and 3-hydroxyacylcoA dehydrogenase activities. The BNF-induced increase inhsp70 levels and conjugation enzyme activities (phase I and phase II)were not modified by handling stress. Indeed handling stress did not affect either hsp 70 levels or conjugation enzyme activities in trout liver. The decrease in hepatic PEPCK activity in the BNF group may be responsible for the attenuation of the increase in liver glucose concentration after a 3 min handling stress in this species, suggesting that BNF affects liver gluconeogenic capacity in this species. Handling stress elicited a plasma cortisol and glucose response in both the shamand BNF group, however, the cortisol response with BNF was erratic compared with the sham, implying alterations in the cortisol dynamics post-stress. These results show fbr the first time that BNF affects cellular metabolic responses to stress and suggests the possibility of using hsp 70 as a biomarker for toxic effects in trout.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 01:31:36