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Titolo:
Microembolic signal monitoring in hemispheric acute ischaemic stroke: A prospective study
Autore:
Serena, J; Segura, T; Castellanos, M; Davalos, A;
Indirizzi:
Hosp Univ Doctor Josep Trueta, Neurol Sect, E-17007 Girona, Spain Hosp Univ Doctor Josep Trueta Girona Spain E-17007 E-17007 Girona, Spain Hosp Univ Doctor Josep Trueta, Stroke Res Unit, E-17007 Girona, Spain HospUniv Doctor Josep Trueta Girona Spain E-17007 E-17007 Girona, Spain
Titolo Testata:
CEREBROVASCULAR DISEASES
fascicolo: 4, volume: 10, anno: 2000,
pagine: 278 - 282
SICI:
1015-9770(200007/08)10:4<278:MSMIHA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTENSITY TRANSIENT SIGNALS; CAROTID-ARTERY STENOSIS; PROSTHETIC CARDIAC VALVES; TRANSCRANIAL DOPPLER; CEREBRAL MICROEMBOLISM; ISCHEMIC STROKE; DISEASE; RISK; EMBOLI; PREVALENCE;
Keywords:
cerebral embolism; ultrasonography; stroke; microembolic signals;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Serena, J Hosp Univ Doctor Josep Trueta, Neurol Sect, E-17007 Girona, Spain Hosp Univ Doctor Josep Trueta Girona Spain E-17007 rona, Spain
Citazione:
J. Serena et al., "Microembolic signal monitoring in hemispheric acute ischaemic stroke: A prospective study", CEREB DIS, 10(4), 2000, pp. 278-282

Abstract

Background and Purpose: There are few data on the occurrence of microembolic signals (MES) in the acute phase of ischaemic stroke. The objective of our work was to systematically study the frequency of MES in nonselected patients with a first-ever hemispheric transient ischemic attack (TIA) or acute cerebral infarction, and to evaluate the clinical usefulness of MES detection. Methods: 182 consecutive patients with hemispheric TIA or acute cerebral infarction, and 54-age-matched healthy controls were studied. Bilateraltranscranial Doppler ultrasound (TCD) monitoring was performed for at least 30 min with a mean time from stroke onset to TCD of 69 h. Stroke severityon admission, early recurrent stroke and dependency on discharge were investigated. Results: MES were detected in 20.5% of patients with arterial sources of embolism, 17.1% of patients with potential sources of cardioembolism and 5% of patients with cryptogenic stroke. They were not registered, however, in lacunar infarctions (p < 0.001). Stroke severity on admission of patients with MES was greater than that of patients without MES (47.1 vs. 19.4% with the Canadian Stroke Scale less than or equal to 6.5; p = 0.009). Early recurrent stroke was more frequent in patients with MES (11.8%) than in those without MES (4.2%) although the difference was not statistically significant. Multiple logistic regression analysis showed that MES increased the risk of dependency on discharge (odds ratio, 4.2; 95% CI, 1.2-14.9; p =0.01) independently of age, stroke severity on admission and presence of an arterial or cardiac embolic source. Conclusions: There is a strong association of MES in the acute phase of stroke with known potential arterial andcardiac embolic sources. MES have an independent predictive Value of poor outcome. Copyright (C) 2000 S. Karger AG. Basel.

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Documento generato il 06/04/20 alle ore 05:46:38