Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The temporal and spatial expressions of neuropeptide Y induced by seizure in the hippocampal complex of gerbil
Autore:
Kang, TC; Park, SH; Park, SK; Lee, JC; Jo, SM; Do, SG; Suh, JG; Oh, YS; Lee, JY; Won, MH;
Indirizzi:
Hallym Univ, Coll Med, Dept Anat, Chunchon 200702, Kangwon, South Korea Hallym Univ Chunchon Kangwon South Korea 200702 702, Kangwon, South Korea Hallym Univ, Coll Med, Dept Biochem, Chunchon 200702, Kangwon, South KoreaHallym Univ Chunchon Kangwon South Korea 200702 702, Kangwon, South Korea
Titolo Testata:
BRAIN RESEARCH
fascicolo: 1-2, volume: 870, anno: 2000,
pagine: 179 - 184
SICI:
0006-8993(20000707)870:1-2<179:TTASEO>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICOTROPIN-RELEASING FACTOR; EPILEPTIC MUTANT RAT; LOBE EPILEPSY; MONGOLIAN GERBIL; SUBSTANCE-P; IMMUNOREACTIVITY; SOMATOSTATIN; PATTERNS; NEURONS; CELLS;
Keywords:
neuropeptide Y; hippocampus; dentate hilus; subiculum; mongolian gerbil; epilepsy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Won, MH Hallym Univ, Coll Med, Dept Anat, Chunchon 200702, Kangwon, South Korea Hallym Univ Chunchon Kangwon South Korea 200702 gwon, South Korea
Citazione:
T.C. Kang et al., "The temporal and spatial expressions of neuropeptide Y induced by seizure in the hippocampal complex of gerbil", BRAIN RES, 870(1-2), 2000, pp. 179-184

Abstract

Recent studies reported changes in neuropeptide Y (NPY) expression inducedby seizures in the experimental epileptic models. However, there have beenfew reports of the alteration of NPY expression in hippocampal complexes of genetic epilepsy models. In the present study, we performed spatial and temporal analyses of NPY expression in the hippocampal complexes of the seizure-resistant (SR) and seizure-sensitive (SS) gerbils, one of the genetic models. In SR gerbils, most NPY+ cells were located at the dentate hilus (DH) and the subiculum (SC). In the pre-seizure group of SS gerbils, neurons in the DH and SC were nearly devoid of NPY immunoreactivity. Interestingly, the acute NPY expressions were observed in these areas of the post-seizure group at 30 min, and its immunoreactivity was declined at 12 h after the onset of seizure. These findings suggest that in seizure, the deficiency of NPY in DH and SC may be one of the factors, and that the acute expression ofNPY after seizure in these areas may be the compensatory response for reduction of seizure activity in this animal. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:40:52