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Titolo:
Orthostatic hypotension and the incidence of coronary heart disease: The atherosclerosis risk in communities study
Autore:
Rose, KM; Tyroler, HA; Nardo, CJ; Arnett, DK; Light, KC; Rosamond, W; Sharrett, AR; Szklo, M;
Indirizzi:
Univ N Carolina, Sch Publ Hlth, Dept Epidemiol, Chapel Hill, NC 27514 USA Univ N Carolina Chapel Hill NC USA 27514 emiol, Chapel Hill, NC 27514 USA Immune Response Corp, Carlsbad, CA USA Immune Response Corp Carlsbad CA USA une Response Corp, Carlsbad, CA USA Univ Minnesota, Sch Publ Hlth, Div Epidemiol, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 demiol, Minneapolis, MN 55455 USA Univ N Carolina, Sch Med, Dept Psychiat, Chapel Hill, NC USA Univ N Carolina Chapel Hill NC USA d, Dept Psychiat, Chapel Hill, NC USA NHLBI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA NHLBI Bethesda MD USA 20892 & Clin Applicat, NIH, Bethesda, MD 20892 USA Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Epidemiol, Baltimore, MD USAJohns Hopkins Univ Baltimore MD USA h, Dept Epidemiol, Baltimore, MD USA
Titolo Testata:
AMERICAN JOURNAL OF HYPERTENSION
fascicolo: 6, volume: 13, anno: 2000,
parte:, 1
pagine: 571 - 578
SICI:
0895-7061(200006)13:6<571:OHATIO>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYSTOLIC BLOOD-PRESSURE; POSTURAL HYPOTENSION; PREVALENCE; EXPERIENCE; HYPERTENSION; INFARCTION;
Keywords:
orthostatic hypotension; CHD; middle-aged;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Rose, KM Univ N Carolina, Sch Publ Hlth, Dept Epidemiol, 137 E Franklin St,Nat BankPlaza,Suite 306, Chapel Hill, NC 27514 USA Univ N Carolina 137 E Franklin St,Nat Bank Plaza,Suite 306 Chapel Hill NC USA 27514
Citazione:
K.M. Rose et al., "Orthostatic hypotension and the incidence of coronary heart disease: The atherosclerosis risk in communities study", AM J HYPERT, 13(6), 2000, pp. 571-578

Abstract

We examined the association between orthostatic hypotension (OH) at baseline examination (1987-1989) and the incidence of coronary heart disease (CHD) over an average of 6 years, among 12,433 black and white middle-aged men and women participating in the Atherosclerosis Risk in Communities (ARIC) study. OH was defined as a SEP decrease greater than or equal to 20 mm Hg ora DBP decrease greater than or equal to 10 mm Hg after changing from supine to standing. CHD events included definite or probable myocardial infarctions (MI), silent MI, and fatal CHD. Five percent of participants had OH. Prevalence increased with advancing age and was more common among those with cardiovascular disease (CVD)-related comorbidities and risk factors. Those with OH had an increased risk of CHD (hazard ratio [HR] = 3.49, 95% confidence interval [CI] = 2.58, 4.73). This association was attenuated after controlling for age, ethnicity, gender, comorbid conditions, and CVD risk factors (HR = 1.85, 95% CI = 1.31, 2.63). Am J Hypertens 2000;13:571-578 (C) 2000 American Journal of Hypertension, Ltd.

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Documento generato il 25/11/20 alle ore 10:28:59