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Titolo:
Primary versus rescue percutaneous corollary intervention in patients withacute myocardial infarction
Autore:
Gimelli, G; Kalra, A; Sabatine, MS; Jang, IK;
Indirizzi:
Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 Cardiol, Boston, MA 02114 USA
Titolo Testata:
ACTA CARDIOLOGICA
fascicolo: 3, volume: 55, anno: 2000,
pagine: 187 - 192
SICI:
0001-5385(200006)55:3<187:PVRPCI>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
TISSUE-PLASMINOGEN-ACTIVATOR; CORONARY-ARTERY DISEASE; IMMEDIATE ANGIOPLASTY; THROMBOLYTIC THERAPY; BALLOON ANGIOPLASTY; RECEPTOR BLOCKADE; TRIAL; ABCIXIMAB; OUTCOMES;
Keywords:
acute myocardial infarction; percutaneous coronary intervention; primary angioplasty; rescue angioplasty; intracoronary stenting; thrombolysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Jang, IK Massachusetts Gen Hosp, Div Cardiol, Bulfinch 105,55 Fruit St, Boston, MA 02114 USA Massachusetts Gen Hosp Bulfinch 105,55 Fruit St Boston MA USA 02114
Citazione:
G. Gimelli et al., "Primary versus rescue percutaneous corollary intervention in patients withacute myocardial infarction", ACT CARDIOL, 55(3), 2000, pp. 187-192

Abstract

Objective - To compare angiographic and clinical outcomes of patients withacute myocardial infarction (AMI) who underwent primary percutaneous coronary intervention (PCI) versus rescue PCI following failed thrombolysis. Background - Patients presenting with AMI are treated either with primary PCI or with thrombolysis, When thrombolysis fails, rescue PCI is performed. Methods and Results - We compared the outcome of 105 consecutive patients with AMI who underwent either primary PCI (60 patients) or rescue PCI (45 patients) between January 1997 and January 1999, The patients were followed for up to 6 months. Time delay to reperfusion was significantly longer in the rescue PCI group (354 vs. 189 min; p < 0.001), The majority of patients received a stent (93%). Glycoprotein (GP) IIb/IIIa inhibitors were used in 53% of patients in the primary PCI group and in 22% in the rescue group. TIMI grade 3 flow was achieved in 93.3% of patients in the primary PCI group and in 88.8% in the rescue group (p = 0.08), Post-procedure ejection fraction was 53% in the primary PCI group and 47% in the rescue group (p = 0.014), A composite endpoint of death, recurrent MI, repeat PCI, coronary artery bypass grafting (CABG) and recurrent angina at 6 months occurred in 35% of the patients in the primary PCI group and 26.7% in the rescue group (p = 0.36),Conclusion - Despite a significant delay to reperfusion and a lower immediate post-procedure ejection fraction, the clinical outcome of patients treated with rescue PCI following failed thrombolysis appears to be similar to that of patients treated with primary PCI at 6 months.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 00:03:09