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Titolo:
Selecting treatments: a decision theoretic approach
Autore:
Claxton, K; Lacey, LF; Walker, SG;
Indirizzi:
Univ London Imperial Coll Sci Technol & Med, London, England Univ London Imperial Coll Sci Technol & Med London England don, England Univ York, York YO1 5DD, N Yorkshire, England Univ York York N Yorkshire England YO1 5DD YO1 5DD, N Yorkshire, England Glaxo Wellcome, Uxbridge, Middx, England Glaxo Wellcome Uxbridge Middx England Wellcome, Uxbridge, Middx, England
Titolo Testata:
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY
, volume: 163, anno: 2000,
parte:, 2
pagine: 211 - 225
SICI:
0964-1998(2000)163:<211:STADTA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
COST-EFFECTIVENESS ANALYSIS; CLINICAL-TRIAL DESIGN; ECONOMIC-ANALYSIS; HEALTH-CARE; ISSUES; UNCERTAINTY; APPRAISAL; ALONGSIDE;
Keywords:
budget constraint; cost-benefit; cost effectiveness; marginal programme; utility;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Walker, SG Univ Bath, Dept Math Sci, Claverton Down, Bath BA2 7AY, Avon, England Univ Bath Claverton Down Bath Avon England BA2 7AY von, England
Citazione:
K. Claxton et al., "Selecting treatments: a decision theoretic approach", J ROY STA A, 163, 2000, pp. 211-225

Abstract

The paper looks at the problem of comparing two treatments, for a particular population of patients, where one is the current standard treatment and the other a possible alternative under investigation. With limited (finite)financial resources the decision whether to replace one by the other will not be based on health benefits alone. This motivates an economic evaluation of the two competing treatments where the cost of any gain in health benefit is scrutinized; it is whether this cost is acceptable to the relevant authorities which decides whether the new treatment can become the standard. We adopt a Bayesian decision theoretic framework in which a utility function is introduced describing the consequences of making a particular decision when the true state of nature is expressed via an unknown parameter theta(this parameter denotes cost, effectiveness, etc.). The treatment providing the maximum posterior expected utility summarizes the decision rule, expectations taken over the posterior distribution of the parameter theta.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 12:45:03