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Titolo:
Centrifugal pumps and heparin-coated circuits in surgical treatment of giant cerebral aneurysms
Autore:
Mesana, T; Collart, F; Caus, T; Pomane, C; Graziani, N; Bruder, N; Dufour, H; Grisoli, F; Monties, JR;
Indirizzi:
Univ Marseille, Timone Hosp, Dept Cardiac Surg, Marseille, France Univ Marseille Marseille France p, Dept Cardiac Surg, Marseille, France Univ Marseille, Timone Hosp, Dept Neurosurg, Marseille, France Univ Marseille Marseille France Hosp, Dept Neurosurg, Marseille, France
Titolo Testata:
ARTIFICIAL ORGANS
fascicolo: 6, volume: 24, anno: 2000,
pagine: 431 - 436
SICI:
0160-564X(200006)24:6<431:CPAHCI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CIRCULATORY ARREST; CARDIOPULMONARY BYPASS; HYPOTHERMIA;
Keywords:
centrifugal pumps; heparin coating; giant cerebral aneurysms; deep hypothermia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Mesana, T Hop Timone Adultes, Serv Chirurg Cardiaque, 264 Rue St Pierre, F-13385 Marseille 05, France Hop Timone Adultes 264 Rue St Pierre MarseilleFrance 05 France
Citazione:
T. Mesana et al., "Centrifugal pumps and heparin-coated circuits in surgical treatment of giant cerebral aneurysms", ARTIF ORGAN, 24(6), 2000, pp. 431-436

Abstract

Giant cerebral aneurysms may be untreatable by conventional neurosurgical techniques. Early attempts to use circulatory assistance and deep hypothermia were abandoned due to hemorrhagic complications. More recently, interestin circulatory support for complex neurosurgical procedures has been renewed. A consecutive series of 8 patients were operated on for giant cerebral aneurysms with the combined use of deep hypothermia. The protocol included careful preoperative cardiovascular assessment, perfect intraoperative synergy between neurosurgical and cardiac teams, minimally invasive peripheral vascular access including two femoral vein (21 F) and single arterial (17 F) femoral cannulation, use of total Carmeda coating on BioMedicus pumps in closed circuits, and reduced heparinization without Protamine reversal. Allcerebral aneurysms were successfully treated through deep hypothermia (15-18 degrees C) as assessed by intraoperative fluoroscopic controls and Doppler vascular assessment. Mean circulatory support time was 174.2 +/- 29.6 min. Circulatory arrest period was 20 +/- 12 min. All patients survived and were extubated within 48 h. No major deficit was observed clinically or on postoperative CT scan. No hemorrhagic complications occurred (mean transfusions was 2.2 blood units). This work supports an extensive use of heparin-coated surfaces for complex circulatory assist techniques, either for cardiacor extra cardiac complex procedures.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 06:41:58