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Titolo:
Perspectives in the utilisation of Fourier-transform infrared spectroscopyof serum in sports medicine - Health monitoring of athletes and preventionof doping
Autore:
Petibois, C; Deleris, G; Cazorla, G;
Indirizzi:
Univ Bordeaux 2, INSERM, U443, Equipe Chim BioOrgan, F-33076 Bordeaux, France Univ Bordeaux 2 Bordeaux France F-33076 oOrgan, F-33076 Bordeaux, France Univ Bordeaux 2, Fac Sports Sci & Phys Educ, Talence, France Univ Bordeaux2 Talence France Sports Sci & Phys Educ, Talence, France
Titolo Testata:
SPORTS MEDICINE
fascicolo: 6, volume: 29, anno: 2000,
pagine: 387 - 396
SICI:
0112-1642(200006)29:6<387:PITUOF>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
ORAL CREATINE SUPPLEMENTATION; HUMAN GROWTH-HORMONE; MIDINFRARED SPECTROSCOPY; CONFORMATIONAL ORDER; HUMAN ERYTHROCYTES; MASS-SPECTROMETRY; IR SPECTROSCOPY; HUMAN BLOOD; CELL-SHAPE; DRUGS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Deleris, G Univ Bordeaux 2, INSERM, U443, Equipe Chim BioOrgan, 146 Rue Leo Saignat, F-33076 Bordeaux, France Univ Bordeaux 2 146 Rue Leo Saignat Bordeaux France F-33076 ce
Citazione:
C. Petibois et al., "Perspectives in the utilisation of Fourier-transform infrared spectroscopyof serum in sports medicine - Health monitoring of athletes and preventionof doping", SPORT MED, 29(6), 2000, pp. 387-396

Abstract

Doping prevention is mainly directed to providing information on the dangers of doping to young athletes and to every profession concerned with athletic performance. Unfortunately, repression is also necessary in the fight against doping. Measurement of performance-enhancing drugs is complex, partly because of the large number of prohibited substances. A number of sophisticated analytical techniques are increasingly being used to provide the maximum detection time window. However, the effectiveness of methods to separate exogenous from endogenous biological molecules and the cost of antidoping analyses makes controls invalid or impossible. Moreover, most athletes, because of the metabolic and psychological stresses caused, legitimately refuse blood testing. It is becoming crucial to introduce new methods in the form of longitudinal health monitoring, since this is probably the most effective tool to prevent the use of doping agents when athletes become overtrained and/or overstressed. This paper describes new methods using Fourier-transform infrared spectroscopy to analyse serum from 50 mu l samples of capillary blood. This technique has been shown to allow determination of the concentration of a wide range of biological molecules in a single microsample with clinically useful accuracy, and to provide a 'discriminatory biomolecular profile' to differentiate individuals on the basis of their physiological status. A specific application of this methodology is to perform longitudinal health monitoring in athletes, allowing prevention of overtraining. It is proposed to apply such methods in longitudinal studies for health monitoring and prevention ofdoping.

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Documento generato il 20/01/21 alle ore 01:40:21