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Titolo:
Murine typhus in South Texas children
Autore:
Fergie, JE; Purcell, K; Wanat, D;
Indirizzi:
Driscoll Childrens Hosp, Corpus Christi, TX 78411 USA Driscoll Childrens Hosp Corpus Christi TX USA 78411 Christi, TX 78411 USA Texas Tech Sch Pharm, Dallas Ft Worth Ctr, Dallas, TX USA Texas Tech Sch Pharm Dallas TX USA , Dallas Ft Worth Ctr, Dallas, TX USA
Titolo Testata:
PEDIATRIC INFECTIOUS DISEASE JOURNAL
fascicolo: 6, volume: 19, anno: 2000,
pagine: 535 - 538
SICI:
0891-3668(200006)19:6<535:MTISTC>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPIDEMIOLOGY; FEVER;
Keywords:
typhus; murine; endemic; South Texas; children;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Fergie, JE Driscoll Childrens Hosp, 3533 S Alameda St, Corpus Christi, TX 78411 USA Driscoll Childrens Hosp 3533 S Alameda St Corpus Christi TX USA 78411
Citazione:
J.E. Fergie et al., "Murine typhus in South Texas children", PEDIAT INF, 19(6), 2000, pp. 535-538

Abstract

Background. Murine typhus is a zoonotic infection caused by Rickettsia typhi, This illness used to be endemic in the southeastern and gulf coast of the United States and is now only rarely reported in South Texas and Southern California. Murine typhus causes a febrile illness with headache and rashthat has been well-described in adults. Objective, To define the epidemiologic and clinical characteristics, laboratory findings, hospital course and response to therapy of children discharged from our hospital with a diagnosis of murine typhus,Methods. Retrospective chart review of all children discharged from Driscoll Children's Hospital, Corpus Christi, TX, from January 1, 1990, to June 30, 1998, with a diagnosis of murine typhus,Patients, Thirty children (17 females) ages 2 to 17 years (mean, 10 +/- 4 years). Results, Eighty percent of the children were admitted between May and November, and 67% had a history of contact with or exposure to a potential animal reservoir. Children were admitted after a mean of 7 +/- 4 days, The mostcommon clinical features were fever 100%, rash 80% and headache 77%, Laboratory abnormalities included elevated erythrocyte sedimentation rate (75%),elevated serum transaminases (67%), hyponatremia (66%) and increased immature leukocytes without leukocytosis (63%), Only one child had leukocytosis and 40% had leukopenia. Defervescence occurred a mean of 35 +/- 19 h after initiation of appropriate antibiotics. Hospitalization lasted for a mean of7 +/- 3 days. There were no readmissions and no patients died as a result of the infection,Conclusions. Despite being rarely reported in this country now, murine typhus continues to be an important cause of fever and hospitalization for children in South Texas. Children with murine typhus develop an illness similar to that reported in adults with fever, rash and headache. Children respond quickly to therapy with doxycycline or tetracycline and recover completely from their illness.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 15:27:52