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Titolo:
High-field quantitative transverse relaxation time, magnetization transferand apparent water diffusion in experimental rat brain tumour
Autore:
Lemaire, L; Franconi, F; Saint-Andre, JP; Roullin, VG; Jallet, P; Le Jeune, JJ;
Indirizzi:
Univ Angers, UPRESA EA 2169 Vectorisat Particulaire, Angers, France Univ Angers Angers France 2169 Vectorisat Particulaire, Angers, France Univ Angers, Serv Commun RMN, Angers, France Univ Angers Angers FranceUniv Angers, Serv Commun RMN, Angers, France CHU Angers, Anat Pathol Lab, Angers, France CHU Angers Angers FranceCHU Angers, Anat Pathol Lab, Angers, France
Titolo Testata:
NMR IN BIOMEDICINE
fascicolo: 3, volume: 13, anno: 2000,
pagine: 116 - 123
SICI:
0952-3480(200005)13:3<116:HQTRTM>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VIVO; TRANSFER CONTRAST; MRI; TESLA;
Keywords:
quantitative MRI; rat-brain tumours; relaxometry; apparent diffusion coefficient; magnetization transfer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Lemaire, L Fac Med, Lab Biophys Med, 2 Rue Haute Reculee,Pavillon Ollivier, F-49045 Angers, France Fac Med 2 Rue Haute Reculee,Pavillon Ollivier Angers France F-49045
Citazione:
L. Lemaire et al., "High-field quantitative transverse relaxation time, magnetization transferand apparent water diffusion in experimental rat brain tumour", NMR BIOMED, 13(3), 2000, pp. 116-123

Abstract

The potential of quantitative parameter images of transverse relaxation time T-2, apparent diffusion coefficient (ADC) and magnetization transfer ratio (MTR) to characterize experimental brain tumours was studied. Necrosis or haemorrhage can be detected using either MTR, ADC or T-2 (necrosis-MTR reduced by 35%, ADC and T-2 increased respectively by 170% and 100% compared with normal brain tissue; haemorrhage-MTR increased by 60%, ADC and T-2 decreased by 40% and 20%, respectively). Normal brain tissue can only be distinguished from tumour on T-2 and MTR parameter images. However, for small tumours (10 mu l), the best contrast is observed with MTR, ca. 30%, whereas for T-2 the contrast is ca. 10%. Copyright (C) 2000 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 23:56:38