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Titolo:
Vestibular compensation modifies the sensitivity of vestibular neurones toinhibitory amino acids
Autore:
Vibert, N; Beraneck, M; Bantikyan, A; Vidal, PP;
Indirizzi:
Univ Sydney, Dept Psychol, Vestibular Res Lab, Sydney, NSW 2006, AustraliaUniv Sydney Sydney NSW Australia 2006 es Lab, Sydney, NSW 2006, Australia Univ Paris 05, Ctr Univ St Peres, Lab Neurobiol Reseaux Sensorimoteurs, CNRS,ESA 7060, F-75270 Paris 06, France Univ Paris 05 Paris France 06 s, CNRS,ESA 7060, F-75270 Paris 06, France Univ Paris 07, Ctr Univ St Peres, Lab Neurobiol Reseaux Sensorimoteurs, CNRS,ESA 7060, F-75270 Paris 06, France Univ Paris 07 Paris France 06 s, CNRS,ESA 7060, F-75270 Paris 06, France
Titolo Testata:
NEUROREPORT
fascicolo: 9, volume: 11, anno: 2000,
pagine: 1921 - 1927
SICI:
0959-4965(20000626)11:9<1921:VCMTSO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRAIN-STEM SLICES; GUINEA-PIG; IN-VITRO; NUCLEUS NEURONS; RECEPTORS; PLASTICITY; RECOVERY; LESIONS; MAMMALS; INVITRO;
Keywords:
brain stem slices; GABA; glycine; guinea-pig; in vitro; medial vestibular nucleus; post-lesion plasticity; vestibular neurochemistry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Vibert, N Univ Sydney, Dept Psychol, Vestibular Res Lab, Sydney, NSW 2006,Australia Univ Sydney Sydney NSW Australia 2006 dney, NSW 2006, Australia
Citazione:
N. Vibert et al., "Vestibular compensation modifies the sensitivity of vestibular neurones toinhibitory amino acids", NEUROREPORT, 11(9), 2000, pp. 1921-1927

Abstract

The progressive disappearance of the postural and oculomotor syndrome triggered by unilateral labyrinthectomy (vestibular compensation) is a model ofplasticity in the adult central nervous system. This recovery may involve modifications of the pharmacological profile of central vestibular neurones, in particular their sensitivity to inhibitory amino acids. We therefore compared the sensitivity of medial vestibular nucleus neurones to glycine and muscimol in slices taken either from control animals, or from guinea-pigslabyrinthectomized 3 days before. We demonstrate that the loss of excitatory inputs experienced by the ipsilesional vestibular neurones induces a decrease in their sensitivity to inhibitory amino acids. These pharmacologicalchanges should facilitate the recovery of a normal balance between the average resting discharge of neurones in both vestibular nuclei. NeuroReport 11:1921-1927 (C) 2000 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 00:25:02