Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Geometry of rubrospinal, rubroolivary, and local circuit neurons in the macaque red nucleus
Autore:
Burman, K; Darian-Smith, C; Darian-Smith, I;
Indirizzi:
Univ Melbourne, Dept Anat & Cell Biol, Brain Res Lab, Parkville, Vic 3052,Australia Univ Melbourne Parkville Vic Australia 3052 Parkville, Vic 3052,Australia
Titolo Testata:
JOURNAL OF COMPARATIVE NEUROLOGY
fascicolo: 2, volume: 423, anno: 2000,
pagine: 197 - 219
SICI:
0021-9967(20000724)423:2<197:GORRAL>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
GABA-GOLD TECHNIQUE; MACACA-FASCICULARIS; WGA-HRP; SYNAPTIC ORGANIZATION; ANTEROGRADE TRANSPORT; ANATOMICAL EVIDENCE; CEREBELLAR NUCLEI; DENDRITIC SPINES; LUCIFER YELLOW; MONKEY;
Keywords:
primate; intracellular labeling; rubral neurons; dendrite morphology; interneurons;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Darian-Smith, I Univ Melbourne, Dept Anat & Cell Biol, Brain Res Lab, Parkville, Vic 3052,Australia Univ Melbourne Parkville Vic Australia 3052 052,Australia
Citazione:
K. Burman et al., "Geometry of rubrospinal, rubroolivary, and local circuit neurons in the macaque red nucleus", J COMP NEUR, 423(2), 2000, pp. 197-219

Abstract

The primate red nucleus consists of three main neuron subpopulations, namely, rubrospinal neurons in the magnocellular nucleus, rubroolivary cells inthe parvocellular nucleus, and local circuit neurons in both subnuclei: Each subpopulation has unique cerebellar and neocortical inputs. The structural framework for the interactions of these rubral subpopulations remains poorly defined and was the focus of this study in six macaques. Somata of rubrospinal neurons, dorsolateral-spinal (DL-spinal) neurons, as defined in the accompanying paper (Burman et al. [2000] J. Comp. Neurol., this issue), and rubroolivary neurons were labeled retrogradely first with Fast Blue injected either into the cervical spinal cord or the inferior olive. The soma/dendrite profiles of selected cells (53 rubrospinal, 19 DL-spinal, and 17 rubroolivary cells) were visualized by the intracellular injection of LuciferYellow/biocytin in fixed slices (400 mu m thick) of midbrain. The descriptive statistics of the somata and the dendritic arborization of each rubral neuron type were established. Projection neuron subpopulations had similar but differentiable soma/dendrite profiles, with four to six slender, spine-bearing dendritic trees radiating out approximate to 400 mu m from the soma. Twelve presumed interneurons, all in the parvocellular nucleus, differed from projection neurons in that they had smaller somata and many slender, spine-bearing segments that constituted the multi-branching dendrite profilethat radiated out approximate to 250 mu m from the soma. A tentative modelof the macaque rubral microcircuitry was developed, and its functional implications were explored. It incorporated 1) the known topography of the nucleus and its connections, 2) our data specifying the soma/dendrite morphology of the three main rubral neuron types, and 3) the ultrastructure reported by other laboratories of intrarubral synaptic connections. J. Comp. Neurol. 423:197-219, 2000. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:13:11