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Titolo:
BRAIN-TUMORS - LOCALIZED H-1 MR-SPECTROSCOPY AT 0.5-T
Autore:
PROST R; HAUGHTON V; LI SJ;
Indirizzi:
MED COLL WISCONSIN,BIOPHYS RES INST,8701 WATERTOWN PLANK RD,POB 26509MILWAUKEE WI 53226 MED COLL WISCONSIN,BIOPHYS RES INST MILWAUKEE WI 53226 MED COLL WISCONSIN,DEPT RADIOL MILWAUKEE WI 53226
Titolo Testata:
Radiology
fascicolo: 1, volume: 204, anno: 1997,
pagine: 235 - 238
SICI:
0033-8419(1997)204:1<235:B-LHMA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAGNETIC-RESONANCE SPECTROSCOPY; MULTIPLE-SCLEROSIS; LESIONS; INVIVO;
Keywords:
BRAIN NEOPLASMS, MR; MAGNETIC RESONANCE (MR), SPECTROSCOPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
R. Prost et al., "BRAIN-TUMORS - LOCALIZED H-1 MR-SPECTROSCOPY AT 0.5-T", Radiology, 204(1), 1997, pp. 235-238

Abstract

PURPOSE: To investigate the feasibility of obtaining clinically useful magnetic resonance (MR) spectra at 0.5 T in cerebral lesions. MATERIALS AND METHODS: Single-voxel localized proton MR spectroscopy was performed at 0.5 T in 18 patients (aged 16-73 years) suspected of having cerebral lesions on MR images who subsequently underwent craniotomy and biopsy and in eight volunteers (aged 21-50 years). The metabolite resonances in the MR spectra were stratified according to the histologicdiagnosis. MR spectra demonstrated resonances for choline-containing compounds (Cho), creatine and phosphocreatine, glutamine and glutamate, N-acetylaspartate (NAA), myo-inositol, and lactate. RESULTS: In 14 of 15 patients with cerebral tumors, the Cho-NAA ratio was increased and was greater than 1. In three patients with nonneoplastic cerebral lesions, the ratio did not exceed 1. In healthy control subjects, the average ratio was 0.54. CONCLUSION: H-1 MR spectroscopy at 0.5 T provides clinically useful information in patients with cerebral lesions.

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Documento generato il 05/12/20 alle ore 01:10:08