Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Nasal nitric oxide is reduced in patients with HIV
Autore:
Palm, J; Lidman, C; Graf, P; Alving, K; Lundberg, J;
Indirizzi:
Karolinska Inst, Dept Physiol & Pharmacol, SE-17177 Stockholm, Sweden Karolinska Inst Stockholm Sweden SE-17177 ol, SE-17177 Stockholm, Sweden Huddinge Univ Hosp, Dept Otorhinolaryngol, S-14186 Huddinge, Sweden Huddinge Univ Hosp Huddinge Sweden S-14186 gol, S-14186 Huddinge, Sweden Huddinge Univ Hosp, Dept Infect Dis, S-14186 Huddinge, Sweden Huddinge Univ Hosp Huddinge Sweden S-14186 Dis, S-14186 Huddinge, Sweden
Titolo Testata:
ACTA OTO-LARYNGOLOGICA
fascicolo: 3, volume: 120, anno: 2000,
pagine: 420 - 423
SICI:
0001-6489(2000)120:3<420:NNOIRI>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXHALED AIR; MUCOCILIARY FUNCTION; ACUTE SINUSITIS; REPLICATION; INFECTION; ARGININE; HUMANS; CELLS; FLOW;
Keywords:
AIDS; exhaled air; HIV; nasal; nitric oxide; oral; sinusitis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Palm, J Karolinska Inst, Dept Physiol & Pharmacol, SE-17177 Stockholm, Sweden Karolinska Inst Stockholm Sweden SE-17177 7177 Stockholm, Sweden
Citazione:
J. Palm et al., "Nasal nitric oxide is reduced in patients with HIV", ACT OTO-LAR, 120(3), 2000, pp. 420-423

Abstract

The gas nitric oxide (NO) is present in high concentrations in human nasalairways. Since NO is known to inhibit the growth of bacteria and viruses, it has been suggested that airborne NO represents the first line of defenceagainst pathogens in the upper airways. Low nasal NO levels have been reported previously in patients susceptible to upper airway infection. Since HIV-positive patients are at risk for respiratory tract infections, includingsinusitis, we studied the levels of NO in the upper and lower airways of these patients. A cross-sectional study with age-matched HIV patients and controls was carried out. Nasal and orally exhaled NO were measured in 31 HIVpatients and 26 controls using a well-established chemiluminescence methoddeveloped for measurements of gaseous NO in the airways. Nasal NO was 21% lower (p < 0.05, Student's t-test) in HIV patients than in controls, whereas orally exhaled NO did not differ between the two groups. We conclude thatnasal NO is reduced in patients with HIV infection. The reduction in nasalNO may contribute to the decreased resistance to airway infections in these patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 22:39:48