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Titolo:
Impact of body weight on urinary electrolytes in urinary stone formers
Autore:
Powell, CR; Stoller, ML; Schwartz, BF; Kane, C; Gentle, DL; Bruce, JE; Leslie, SW;
Indirizzi:
Univ Calif San Francisco, Dept Urol, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Naval Ctr San Diego, Dept Urol, San Diego, CA USA Naval Ctr San Diego SanDiego CA USA Diego, Dept Urol, San Diego, CA USA Tripler Army Med Ctr, Honolulu, HI 96859 USA Tripler Army Med Ctr Honolulu HI USA 96859 ed Ctr, Honolulu, HI 96859 USA Univ Cincinnati, Cincinnati, OH USA Univ Cincinnati Cincinnati OH USAUniv Cincinnati, Cincinnati, OH USA Lab Corp, Loraine, OH USA Lab Corp Loraine OH USALab Corp, Loraine, OH USA
Titolo Testata:
UROLOGY
fascicolo: 6, volume: 55, anno: 2000,
pagine: 825 - 830
SICI:
0090-4295(200006)55:6<825:IOBWOU>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIETARY-INTAKE; PARATHYROID-HORMONE; URATE EXCRETION; MORBID-OBESITY; ANIMAL PROTEIN; URIC-ACID; CALCIUM; METABOLISM; BYPASS; WOMEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Stoller, ML Univ Calif San Francisco, Dept Urol, U-575, San Francisco, CA 94143 USA Univ Calif San Francisco U-575 San Francisco CA USA 94143 USA
Citazione:
C.R. Powell et al., "Impact of body weight on urinary electrolytes in urinary stone formers", UROLOGY, 55(6), 2000, pp. 825-830

Abstract

Objectives. Obesity increases the risk of developing chronic medical conditions such as diabetes mellitus, hypertension, and coronary artery disease. We performed a retrospective review of a large data base on urinary stonesto determine if differences are found in urine and serum chemistries amongobese and nonobese stone-forming patients. The effect of body weight on stone recurrence among urinary stone formers was also determined. Methods. A national data base containing serum biochemical profiles, 24-hour urine specimens, and standardized questionnaires was retrospectively evaluated from 5942 consecutive patients with urinary stone disease. Stone-forming patients were classified by body weight: nonobese men, less than 100 kg and nonobese women, less than 85 kg; intermediate men, 100 to 120 kg and intermediate women, 85 to 100 kg; and obese men, more than 120 kg and obesewomen, more than 100 kg. Results. Obese stone formers comprised 6.8% (n = 404) of the patient population. The mean weight in the nonobese and obese groups was 81 kg versus 134 kg, respectively, for men and 64 kg versus 112 kg, respectively, for women. Obese patients represented 3.8% of the male and 12.6% of the female population. Obese patients had increased urinary excretion of sodium, calcium, magnesium, citrate, sulfate, phosphate, oxalate, uric acid, and cystine; obesity was associated with increased urinary volumes and urine osmolality compared with the nonobese patients. Obese men had increased concentration ofurinary sodium, oxalate, uric acid, sulfate, and phosphate when corrected for urinary volume. Obese women had increased concentrations of sodium, uric acid, sulfate, phosphate, and cystine. The mean number of stone episodes in nonobese versus obese men was similar (3.55 and 3.56), whereas mean stone episodes were 2.93 and 3.38 (P = 0.045) for nonobese versus obese women. Conclusions. Among known stone formers, obesity is associated with unique changes in both serum and urinary chemistries. These changes are associatedwith an increased incidence of urinary stone episodes in obese women but not in obese men. UROLOGY 55: 825-830, 2000. (C) 2000, Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 10:19:43