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Titolo:
D2 dopamine receptor blockade immediately post-training enhances retentionin hidden and visible platform versions of the water maze
Autore:
Setlow, B; McGaugh, JL;
Indirizzi:
Univ Calif Irvine, Ctr Neurobiol Learning & Memory, Irvine, CA 92697 USA Univ Calif Irvine Irvine CA USA 92697 ning & Memory, Irvine, CA 92697 USA Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA 92697 USA Univ CalifIrvine Irvine CA USA 92697 obiol & Behav, Irvine, CA 92697 USA
Titolo Testata:
LEARNING & MEMORY
fascicolo: 3, volume: 7, anno: 2000,
pagine: 187 - 191
SICI:
1072-0502(200005/06)7:3<187:DDRBIP>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONDITIONED PLACE PREFERENCE; MEMORY CONSOLIDATION; NUCLEUS-ACCUMBENS; CAUDATE-PUTAMEN; AGONISTS; ANTAGONISTS; SULPIRIDE; MICE; HIPPOCAMPUS; RELEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Setlow, B Univ Calif Irvine, Ctr Neurobiol Learning & Memory, Irvine, CA 92697 USA Univ Calif Irvine Irvine CA USA 92697 ory, Irvine, CA 92697 USA
Citazione:
B. Setlow e J.L. McGaugh, "D2 dopamine receptor blockade immediately post-training enhances retentionin hidden and visible platform versions of the water maze", LEARN MEM, 7(3), 2000, pp. 187-191

Abstract

Considerable evidence shows that post-training administration of dopamine agonists can enhance memory through actions on consolidation processes, butrelatively little is known regarding the effects of dopamine antagonists on consolidation. These experiments investigated the effects of post-training systemic administration of the D2 receptor antagonist sulpiride on consolidation of memory for two versions of the Morris water maze task. Rats trained in either the hidden (spatial) or visible (cued) platform version received a subcutaneous injection of sulpiride or vehicle immediately following training. Retention testing 48 hr later revealed that relative to vehicle controls, sulpiride reduced platform latencies in both task versions, suggesting that like dopamine agonists, sulpiride can also have memory-enhancing effects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 00:28:05