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Titolo:
T1A AND T1B BREAST-CANCER - A 12-YEAR EXPERIENCE
Autore:
VISSER TJ; HAAN M; KEIDAN R; LUCAS R; INGOLD J; GLOVER J; RIGGO P;
Indirizzi:
WILLIAM BEAUMONT HOSP,DEPT SURG,3601 W 13 MILE RD ROYAL OAK MI 48073
Titolo Testata:
The American surgeon
fascicolo: 7, volume: 63, anno: 1997,
pagine: 621 - 626
SICI:
0003-1348(1997)63:7<621:TATB-A>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
RANDOMIZED CLINICAL-TRIAL; LYMPH-NODE DISSECTION; AXILLARY DISSECTION; RADICAL MASTECTOMY; CARCINOMA; CONSERVATION; METASTASES; THERAPY; SIZE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
T.J. Visser et al., "T1A AND T1B BREAST-CANCER - A 12-YEAR EXPERIENCE", The American surgeon, 63(7), 1997, pp. 621-626

Abstract

To understand the prevalence of axillary node metastasis and survivalof patients with T1a and T1b breast cancers, we reviewed the experience at a large community hospital. All patients in the William BeaumontHospital tumor registry with breast cancer treated between January 1983 and November 1995 were evaluated for tumor size, age, cell type, and the presence or absence of axillary node disease. Long-term survivalwas evaluated in patients treated between 1983 and 1992. The patientswere defined as premenopausal or postmenopausal based on age (49 years or less, premenopausal; 50 years or greater, postmenopausal). Of the4590 patients treated for breast cancer from 1983 to 1995, 915 had tumors 1.0 cm or less in size. Of 181 patients who had T1a cancer, 27 were premenopausal, and 154 were postmenopausal. Twenty-three premenopausal patients had axillary lymph nodes examined, two (8.7%) had histologically positive lymph nodes. Of 118 postmenopausal patients who had axillary nodes examined, six (5.1%) had positive lymph nodes. In those with T1b tumors, 130 patients were premenopausal; 604 patients were postmenopausal. Of these, 119 premenopausal patients had axillary nodes examined, and 29 (24.4%) had positive lymph nodes. Of 464 postmenopausal patients who had axillary nodes examined, 66 (14.2%) had positive nodes. The overall, disease-free, and tumor-specific survival rates forpatients with T1a tumors were 93.8, 87.5, and 93.8 per cent (premenopausal) and 86.2, 95.4, and 95.4 per cent (postmenopausal), respectively. These survival rates for patients with T1b tumors were 87.8, 87.8, and 91.1 per rent (premenopausal) and 82.9, 88.5, and 92.9 per cent (postmenopausal), respectively. Premenopausal T1b patients had a higher rate of nodal involvement than postmenopausal T1b patients (P = 0.011). Postmenopausal T1b patients had a higher nodal metastasis rate than postmenopausal T1a patients (P = 0.01). T1b patients had a higher rateof axillary involvement than did T1a patients (P = 0.0018). Based on the rate of axillary lymph node metastasis and survival statistics, there may be a role for axillary node dissection in select patients withtumors less than 1.0 cm. in size.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 18:51:55