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Titolo:
Prevalence and significance of focal sources of atrial arrhythmia in patients undergoing cardioversion of persistent atrial fibrillation
Autore:
Todd, DM; Fynn, SP; Hobbs, WJ; Fitzpatrick, AP; Garratt, CJ;
Indirizzi:
Manchester Royal Infirm, Manchester Heart Ctr, Manchester M13 9WL, Lancs, England Manchester Royal Infirm Manchester Lancs England M13 9WL , Lancs, England
Titolo Testata:
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
fascicolo: 6, volume: 11, anno: 2000,
pagine: 616 - 622
SICI:
1045-3873(200006)11:6<616:PASOFS>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOW-ENERGY CARDIOVERSION; SINUS RHYTHM; RADIOFREQUENCY ABLATION; EXTERNAL CARDIOVERSION; DEFIBRILLATION; MAINTENANCE; REINITIATION; PREDICTORS; IMMEDIATE; SOTALOL;
Keywords:
atrial fibrillation; cardioversion; tachyarrhythmias;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Garratt, CJ Manchester Royal Infirm, Manchester Heart Ctr, Oxford Rd, Manchester M13 9WL, Lancs, England Manchester Royal Infirm Oxford Rd ManchesterLancs England M13 9WL
Citazione:
D.M. Todd et al., "Prevalence and significance of focal sources of atrial arrhythmia in patients undergoing cardioversion of persistent atrial fibrillation", J CARD ELEC, 11(6), 2000, pp. 616-622

Abstract

Introduction: Recent reports have highlighted the importance of focal atrial arthythmias as a curable cause for a group of patients with frequently recurrent paroxysmal atrial fibrillation (AF). The importance of this arrhythmia mechanism in the general population of patients with persistent AF is unknown. Methods and Results: After successful internal cardioversion of 50 consecutive patients with persistent AF (mean age 60 years, mean duration of AF 26months), endocardial activity in the immediate posteardioversion period was analyzed for the presence of focal atrial activity, Postcardioversion atrial arrhythmias were considered to be focal if there was evidence of a localized source of repetitive early atrial activation, either in the form of ii) self-terminating monomorphic atrial tachycardia (at least five beats) or(2) recurrences of AF with an initial atrial activation sequence (first five beats) that was both monomorphic and reproducible with repeated recurrences, Evidence for a focal atrial arrhythmia was present in 20 of the total group of 50 patients (40 %). Multivariate analysis of clinical characteristics revealed the diagnosis of lone AF as the only independent predictor of a focal source of AF (P = 0.028), Thirty-nine patients were discharged fromhospital in sinus rhythm, At 1-month follow-up, 25 (64%) of these 39 patients had suffered AF recurrence. The only significant predictor of AF recurrence was evidence of a focal source of atrial arrhythmia immediately after cardioversion, with a relative risk of 1.73 (range 1.1 to 2.7; P = 0.015). Conclusion: Focal atrial arrhythmias are common in patients presenting with "idiopathic" persistent AF, suggesting a possible causative role in the generation of this common arrhythmia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/10/20 alle ore 05:04:10