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Titolo:
All that scallops is not celiac disease
Autore:
Shah, VH; Rotterdam, H; Kotler, DP; Fasano, A; Green, PHR;
Indirizzi:
Columbia Univ Coll Phys & Surg, Div Gastroenterol, New York, NY 10032 USA Columbia Univ Coll Phys & Surg New York NY USA 10032 w York, NY 10032 USA Columbia Univ Coll Phys & Surg, Dept Surg Pathol, New York, NY 10032 USA Columbia Univ Coll Phys & Surg New York NY USA 10032 w York, NY 10032 USA Univ Maryland, Sch Med, Div Pediat Gastroenterol & Nutr, Baltimore, MD 21201 USA Univ Maryland Baltimore MD USA 21201 erol & Nutr, Baltimore, MD 21201 USA
Titolo Testata:
GASTROINTESTINAL ENDOSCOPY
fascicolo: 6, volume: 51, anno: 2000,
pagine: 717 - 720
SICI:
0016-5107(200006)51:6<717:ATSINC>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENDOSCOPIC DEMONSTRATION; VALVULAE CONNIVENTES; DUODENAL FOLDS; TROPICAL-SPRUE; ATROPHY; MUCOSA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Green, PHR Columbia Presbyterian Med Ctr, 161 Ft Washington Ave,Rm 645, New York, NY 10032 USA Columbia Presbyterian Med Ctr 161 Ft Washington Ave,Rm645 New York NY USA 10032
Citazione:
V.H. Shah et al., "All that scallops is not celiac disease", GASTROIN EN, 51(6), 2000, pp. 717-720

Abstract

Background: Scalloping of duodenal folds as well as a mosaic mucosal pattern, decreased folds, and increased vascularity are markers of duodenal mucosal injury, the most common cause being celiac disease. We have recognized scalloping in patients with a variety of conditions other than celiac disease. Methods: Clinical, endoscopic and histologic data were reviewed from selected patients with endoscopically visualized scalloped folds along with testing for endomysial antibodies. Biopsy specimens were examined histologically for villous:crypt ratio, intraepithelial lymphocytes, and inflammation. Results: Thirteen patients with scalloped folds underwent endoscopy for the following reasons: family history of celiac disease and osteoporosis, gastrointestinal bleeding, dyspepsia (2), B-12/folate deficiency (4), and diarrhea (8). Histologic examination was abnormal in all but 1 patient. Villousatrophy or flattening as evidenced by reduced villous:crypt ratio was seenin 11 of 13 patients. Other abnormalities were edematous or broadened villi (10), intraepithelial lymphocytosis (7), and infiltration of lamina propria (6). An infectious organism was identified in 6 patients (46%), Celiac disease was excluded by the lack of specific biopsy findings combined with endomysial antibody testing. Final diagnoses were normal (1), eosinophilic enteritis (1), giardiasis (1), tropical sprue (4), human immunodeficiency virus-related diseases (6) including human immunodeficiency virus enteropathy(1). Conclusion: We conclude that scalloping is not specific for celiac diseasebut rather a predictor of mucosal disease as evidenced by villous atrophy,widening, and edema.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 03:04:14