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Titolo:
Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis
Autore:
Turkdogan-Sozuer, D; Ozek, MM; Sav, A; Dincer, A; Pamir, MN;
Indirizzi:
Marmara Univ, Inst Neurol Sci, Dept Pediat Neurol, Istanbul, Turkey Marmara Univ Istanbul Turkey Sci, Dept Pediat Neurol, Istanbul, Turkey Marmara Univ, Inst Neurol Sci, Dept Neurosurg, Istanbul, Turkey Marmara Univ Istanbul Turkey urol Sci, Dept Neurosurg, Istanbul, Turkey Marmara Univ, Inst Neurol Sci, Dept Pathol, Istanbul, Turkey Marmara UnivIstanbul Turkey Neurol Sci, Dept Pathol, Istanbul, Turkey Radyomar MR Ctr, Istanbul, Turkey Radyomar MR Ctr Istanbul TurkeyRadyomar MR Ctr, Istanbul, Turkey
Titolo Testata:
EUROPEAN RADIOLOGY
fascicolo: 6, volume: 10, anno: 2000,
pagine: 962 - 966
SICI:
0938-7994(2000)10:6<962:SMAMSW>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
STATUS EPILEPTICUS; BRAIN-TUMORS; SPECTROSCOPY;
Keywords:
Rasmussen's syndrome; neuroimaging early findings; myoinositol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Turkdogan-Sozuer, D Atakoy 9 Kisim B7 D-6, TR-34750 Istanbul, Turkey Atakoy 9 Kisim B7 D-6 Istanbul Turkey TR-34750 urkey
Citazione:
D. Turkdogan-Sozuer et al., "Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis", EUR RADIOL, 10(6), 2000, pp. 962-966

Abstract

Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 19:33:20