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Titolo:
Multicentric study on malignant pleural mesothelioma and non-occupational exposure to asbestos
Autore:
Magnani, C; Agudo, A; Gonzalez, CA; Andrion, A; Calleja, A; Chellini, E; Dalmasso, P; Escolar, A; Hernandez, S; Ivaldi, C; Mirabelli, D; Ramirez, J; Turuguet, D; Usel, M; Terracini, B;
Indirizzi:
S Giovanni B Hosp, Canc Epidemiol Unit, Turin, Italy S Giovanni B Hosp Turin Italy B Hosp, Canc Epidemiol Unit, Turin, Italy Reg Ctr Canc Epidemiol & Prevent, Turin, Italy Reg Ctr Canc Epidemiol & Prevent Turin Italy ol & Prevent, Turin, Italy Cataian Inst Oncol, ICO, Dept Epidemiol & Canc Registrat, E-08907 Lhospitalet De Llobregat, Spain Cataian Inst Oncol Lhospitalet De Llobregat SpainE-08907 obregat, Spain Osped Martini, Dept Pathol, Turin, Italy Osped Martini Turin ItalyOsped Martini, Dept Pathol, Turin, Italy CSCST, Barcelona, Spain CSCST Barcelona SpainCSCST, Barcelona, Spain AO Careggi, Ctr Study & Prevent Canc Firenze, CSPO, Epidemiol Unit, Florence, Italy AO Careggi Florence Italy irenze, CSPO, Epidemiol Unit, Florence, Italy Univ Cadiz, Hosp Puerta Mar, Dept Prevent Med & Publ Hlth, Cadiz, Spain Univ Cadiz Cadiz Spain Mar, Dept Prevent Med & Publ Hlth, Cadiz, Spain Agcy Environm Protect Piemonte, ARPA, Turin, Italy Agcy Environm Protect Piemonte Turin Italy Piemonte, ARPA, Turin, Italy Hosp Clin Barcelona, Dept Pathol, Barcelona, Spain Hosp Clin Barcelona Barcelona Spain lona, Dept Pathol, Barcelona, Spain Inst Nacl Seguridad & Higiene & Trabajo, Former Documentat Serv, Barcelona, Spain Inst Nacl Seguridad & Higiene & Trabajo Barcelona Spain arcelona, Spain CSIC, Ctr Invest Desarrollo Barcelona, Barcelona, Spain CSIC Barcelona Spain Ctr Invest Desarrollo Barcelona, Barcelona, Spain Geneva Med Inspectorate Factories, OCIRT, Geneva, Switzerland Geneva Med Inspectorate Factories Geneva Switzerland eneva, Switzerland Geneva Canc Registry, Geneva, Switzerland Geneva Canc Registry Geneva Switzerland c Registry, Geneva, Switzerland
Titolo Testata:
BRITISH JOURNAL OF CANCER
fascicolo: 1, volume: 83, anno: 2000,
pagine: 104 - 111
SICI:
0007-0920(200007)83:1<104:MSOMPM>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONOCCUPATIONAL EXPOSURE; CASALE-MONFERRATO; TREMOLITE;
Keywords:
asbestos; environmental exposure; mesothelioma; case-control studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Agudo, A S Giovanni B Hosp, Canc Epidemiol Unit, Turin, Italy S Giovanni BHosp Turin Italy anc Epidemiol Unit, Turin, Italy
Citazione:
C. Magnani et al., "Multicentric study on malignant pleural mesothelioma and non-occupational exposure to asbestos", BR J CANC, 83(1), 2000, pp. 104-111

Abstract

Insufficient evidence exists on the risk of pleural mesothelioma from non-occupational exposure to asbestos. A population-based case-control study was carried out in six areas from Italy, Spain and Switzerland. Information was collected for 215 new histologically confirmed cases and 448 controls. Apanel of industrial hygienists assessed asbestos exposure separately for occupational, domestic and environmental sources. Classification of domesticand environmental exposure was based on a complete residential history, presence and use of asbestos at home, asbestos industrial activities in the surrounding area, and their distance from the dwelling, In 53 cases and 232 controls without evidence of occupational exposure to asbestos, moderate orhigh probability of domestic exposure was associated with an increased risk adjusted by age and sex: odds ratio (OR) 4.81, 95% confidence interval (CI) 1.8-13.1. This corresponds to three situations: cleaning asbestos-contaminated clothes, handling asbestos material and presence of asbestos material susceptible to damage. The estimated OR for high probability of environmental exposure (living within 2000 m of asbestos mines, asbestos cement plants, asbestos textiles, shipyards, or brakes factories) was 11.5 (95% CI 3.5-38.2). Living between 2000 and 5000 m from asbestos industries or within 500 m of industries using asbestos could also be associated with an increased risk. A dose-response pattern appeared with intensity of both sources of exposure. It is suggested that low-dose exposure to asbestos at home or in the general environment carries a measurable risk of malignant pleural mesothelioma. (C) 2000 Cancer Research Campaign.

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Documento generato il 02/12/20 alle ore 14:37:06