Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Single word reading in developmental stutterers and fluent speakers
Autore:
Salmelin, R; Schnitzler, A; Schmitz, F; Freund, HJ;
Indirizzi:
Helsinki Univ Technol, Low Temp Lab, Brain Res Unit, FIN-02015 Espoo, Finland Helsinki Univ Technol Espoo Finland FIN-02015 , FIN-02015 Espoo, Finland Univ Dusseldorf, Dept Neurol, D-4000 Dusseldorf, Germany Univ Dusseldorf Dusseldorf Germany D-4000 ol, D-4000 Dusseldorf, Germany
Titolo Testata:
BRAIN
, volume: 123, anno: 2000,
parte:, 6
pagine: 1184 - 1202
SICI:
0006-8950(200006)123:<1184:SWRIDS>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; PRIMARY SOMATOSENSORY CORTEX; MEDIAL TEMPORAL-LOBE; PRIMARY MOTOR CORTEX; RIGHT-HEMISPHERE; HUMAN BRAIN; INTRACORTICAL PROJECTIONS; VIBRISSAE REPRESENTATION; FUNCTIONAL-ORGANIZATION; SPEECH ARTICULATION;
Keywords:
human; magnetoencephalography; language disorders; speech production; reading;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
91
Recensione:
Indirizzi per estratti:
Indirizzo: Salmelin, R Helsinki Univ Technol, Low Temp Lab, Brain Res Unit, POB 2200,FIN-02015 Espoo, Finland Helsinki Univ Technol POB 2200 Espoo Finland FIN-02015 inland
Citazione:
R. Salmelin et al., "Single word reading in developmental stutterers and fluent speakers", BRAIN, 123, 2000, pp. 1184-1202

Abstract

Ten fluent speakers and nine developmental stutterers read isolated nouns aloud in a delayed reading paradigm. Cortical activation sequences were mapped with a whole-head magnetoencephalography system. The stutterers were mostly fluent in this task. Although the overt performance was essentially identical in the two groups, the cortical activation patterns showed clear differences, both in the evoked responses, time-locked to word presentation and mouth movement onset, and in task-related suppression of 20-Hz oscillations. Within the first 400 ms after seeing the word, processing in fluent speakers advanced from the left inferior frontal cortex (articulatory programming) to the left lateral central sulcus and dorsal premotor cortex (motor preparation). This sequence was reversed in the stutterers, who showed an early left motor cortex activation followed by a delayed left inferior frontal signal. Stutterers thus appeared to initiate motor programmes before preparation of the articulatory code. During speech production, the right motor/premotor cortex generated consistent evoked activation in fluent speakersbut was silent in stutterers. On the other hand, suppression of motor cortical 20-Hz rhythm, reflecting task-related neuronal processing, occurred bilaterally in both groups. Moreover, the suppression was right-hemisphere dominant in stutterers, as opposed to left-hemisphere dominant in fluent speakers. Accordingly, the right frontal cortex of stutterers was highly activeduring speech production but did not generate synchronous time-locked responses. The speech-related 20-Hz suppression concentrated in the mouth area in fluent speakers, but was evident in both the hand and mouth areas in stutterers. These findings may reflect imprecise functional connectivity within the right frontal cortex and incomplete segregation between the adjacent hand and mouth motor representations in stutterers during speech production. A network including the left inferior frontal cortex and the right motor/premotor cortex, likely to be relevant in merging linguistic and affective prosody with articulation during fluent speech, thus appears to be partly dysfunctional in developmental stutterers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 18:58:06