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Titolo:
Normocalcemic hyperparathyroidism in Vietnamese immigrants living in southern California
Autore:
Luong, KVQ; Nguyen, LTH;
Indirizzi:
Vietnamese Amer Med Res Fdn, Westminster, CA USA Vietnamese Amer Med Res Fdn Westminster CA USA Fdn, Westminster, CA USA
Titolo Testata:
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
fascicolo: 6, volume: 319, anno: 2000,
pagine: 380 - 384
SICI:
0002-9629(200006)319:6<380:NHIVIL>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARATHYROID ADENOMAS; CHROMOSOME-ABNORMALITIES; MULTICELLULAR ORIGIN; SEASON; BIRTH; GENE;
Keywords:
hyperparathyroidism; Vietnamese;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Luong, KVQ 9188 Bolsa Ave, Westminster, CA 92683 USA 9188 Bolsa Ave Westminster CA USA 92683 tminster, CA 92683 USA
Citazione:
K.V.Q. Luong e L.T.H. Nguyen, "Normocalcemic hyperparathyroidism in Vietnamese immigrants living in southern California", AM J MED SC, 319(6), 2000, pp. 380-384

Abstract

Objective: To characterize the normocalcemic hyperparathyroidism in Vietnamese immigrants living in southern California. Methods: Of 14 Vietnamese patients with primary hyperparathyroidism who were observed between 1991 and 1996, 50% (7 patients; 2 men and 5 women) had normal and/or fluctuating levels of serum total calcium. When the serum calcium was corrected for the albumin, the "corrected" calcium was lower than the measured serum total calcium. Their mean age was 56.4 +/- 11.4 years. All patients had normal serum levels of albumin and serum phosphate. Results: Women were affected more often than men by a ratio of 5:2. The serum-ionized calcium as well as intactPTH were increased in all patients. Five patients underwent surgery with confirmation of parathyroid adenomas. Two patients refused surgery. They didnot have osteitis fibrosa cystica by radiological examination. One patienthad low plasma levels of 25-hydroxyvitamin D. Five of 7 normocalcemic patients (70%) were born in the month of December compared with 2 of seven hypercalcemic patients (30%). Conclusion: The blood ionized calcium and intact parathyroid hormone are necessary for confirmation of normocalcemic hyperparathyroidism. Most of our normocalcemic hyperparathyroid patients (70%) were born in the month of December. We postulate that a combination of exposure to solar ultraviolet light during the formation of the fetal parathyroid glands and stimulation from low vitamin D levels in the wintertime may be related to the development of hyperparathyroidism. However, it is difficult to prove a definite correlation between normocalcemic hyperparathyroidism and their month of birth (December), especially when these observations wereseen in a small group of patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 02:42:32