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Titolo:
Inhibitory effect of gurmarin on palatal taste responses to amino acids inthe rat
Autore:
Harada, S; Kasahara, Y;
Indirizzi:
Kagoshima Univ, Sch Dent, Dept Oral Physiol, Kagoshima 8908544, Japan Kagoshima Univ Kagoshima Japan 8908544 Physiol, Kagoshima 8908544, Japan
Titolo Testata:
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
fascicolo: 6, volume: 278, anno: 2000,
pagine: R1513 - R1517
SICI:
0363-6119(200006)278:6<R1513:IEOGOP>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
GREATER SUPERFICIAL PETROSAL; SWEET-TASTE; GUSTATORY RESPONSES; GYMNEMA-SYLVESTRE; PEPTIDE GURMARIN; STIMULI; MICE; QUALITIES; HAMSTERS; LEAVES;
Keywords:
greater superficial petrosal nerve; soft palate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Harada, S Kagoshima Univ, Sch Dent, Dept Oral Physiol, 8-35-1 Sakuragaoka,Kagoshima8908544, Japan Kagoshima Univ 8-35-1 Sakuragaoka Kagoshima Japan8908544 Japan
Citazione:
S. Harada e Y. Kasahara, "Inhibitory effect of gurmarin on palatal taste responses to amino acids inthe rat", AM J P-REG, 278(6), 2000, pp. R1513-R1517

Abstract

Gurmarin (10 mu g/ml), a protein extracted from Gymnema sylvestre, depressed significantly (40-50%) the phasic taste responses to sugars (sucrose, fructose, lactose, and maltose) and saccharin sodium recorded from the greater superficial petrosal nerve (GSP) innervating palatal taste buds in the rat. However, no significant effect of gurmarin was observed for taste responses to NaCl, HCl, and quinine hydrochloride. Phasic responses to D-amino acids that taste sweet to humans (His, Asn, Phe, Gln) were also depressed, but gurmarin treatment was without significant effect on taste responses to D-Trp and D-Ala, six L-amino acids (His, Asn, Phe, Gln, Trp, and Ala), and two basic amino acid HCl salts (Arg and Lys). With the exception of D-Trp, these inhibitory effects of gurmarin on GSP taste responses were related to the rat's preference for these substances.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/08/20 alle ore 20:15:54