Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Pharmacoepidemiology: definition, difficulties, methodology
Autore:
Begaud, B; Dangoumau, J;
Indirizzi:
Univ Victor Segalen Bordeax 2, CHU Bordeaux,Hop Pellegrin, Ctr Pharmacovigilance, Dept Pharmacol, F-33076 Bordeaux, France Univ Victor Segalen Bordeax 2 Bordeaux France F-33076 6 Bordeaux, France
Titolo Testata:
THERAPIE
fascicolo: 1, volume: 55, anno: 2000,
pagine: 113 - 117
SICI:
0040-5957(200001/02)55:1<113:PDDM>2.0.ZU;2-#
Fonte:
ISI
Lingua:
FRE
Keywords:
pharmacovigilance; pharmacoepidemiology; drug; causality; bias;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
0
Recensione:
Indirizzi per estratti:
Indirizzo: Begaud, B Univ Victor Segalen Bordeax 2, CHU Bordeaux,Hop Pellegrin, Ctr Pharmacovigilance, Dept Pharmacol, Carreire Bat 1A Nord, F-33076 Bordeaux, France Univ Victor Segalen Bordeax 2 Carreire Bat 1A Nord Bordeaux France F-33076
Citazione:
B. Begaud e J. Dangoumau, "Pharmacoepidemiology: definition, difficulties, methodology", THERAPIE, 55(1), 2000, pp. 113-117

Abstract

Pharmacoepidemiology aims to complete the evaluation of drugs made before approval, by providing reliable information concerning effectiveness, safety and utilization of medicines in realistic conditions. The goal may be only descriptive or aetiological. In the latter, the conclusions from observational studies can be jeopardized by systematic errors and cannot achieve the robustness of experimental designs. According to directionality, three main types Of studies can be identified: cross-sectional, prospective and retrospective. Prospective and retrospective studies can be based on a single group (descriptive studies) or include a reference group (comparative or aetiologic studies). The interest of prospective studies is reduced when (1) the incidence of the considered event becomes low or (2) one intends to assess the effects of various causal factors. Retrospective studies are approaching their limits when (1) the prevalence of the exposure is low in the source-population or (2) several events or outcomes are concerned.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:35:39