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Titolo:
Prepulse inhibition of the blink reflex by laser stimuli in normal humans
Autore:
Valls-Sole, J; Veciana, M; Serra, J; Cruccu, G; Romaniello, A;
Indirizzi:
Univ Barcelona, Hosp Clin, Serv Neurol,Unitat EMG, Inst Invest Biomed August Pi & Sunyer, E-08036 Barcelona, Spain Univ Barcelona Barcelona Spain E-08036 Sunyer, E-08036 Barcelona, Spain Bellvitge Hosp, Serv Neurol, Barcelona, Spain Bellvitge Hosp Barcelona Spain itge Hosp, Serv Neurol, Barcelona, Spain Clin Univ Rome La Sapienza, Serv Neurol, Rome, Italy Clin Univ Rome La Sapienza Rome Italy apienza, Serv Neurol, Rome, Italy
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 2, volume: 286, anno: 2000,
pagine: 79 - 82
SICI:
0304-3940(20000602)286:2<79:PIOTBR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACOUSTIC STARTLE RESPONSE; PAIN; RAT; MODULATION; MEDIATION; AFFERENTS; NEURONS; DISEASE; TRACT;
Keywords:
laser; blink reflex; prepulse inhibition; brainstem;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Valls-Sole, J Univ Barcelona, Hosp Clin, Serv Neurol,Unitat EMG, Inst Invest Biomed August Pi & Sunyer, Villarroel 170, E-08036 Barcelona, Spain UnivBarcelona Villarroel 170 Barcelona Spain E-08036 Spain
Citazione:
J. Valls-Sole et al., "Prepulse inhibition of the blink reflex by laser stimuli in normal humans", NEUROSCI L, 286(2), 2000, pp. 79-82

Abstract

The subcortical integrative effects of laser-induced activation of pain ascending tracts were examined in 11 healthy volunteers, aged 22-52 years. Subjects underwent either CO2 laser stimulation at the dorsum of the hand, electrical stimulation of digital nerves at the 3rd finger, or mechanical taps to the first dorsal interosseous space, preceding a blink reflex elicitedby a supraorbital nerve electrical stimulus. The percentage inhibition induced in the R2 response of the blink reflex was similar for the three different stimulus modalities, but occurred at a different time interval. Compared to control trials, the R2 response of the test trials was a mean of 23.1% at the interval of 250 ms with laser stimuli, 17.4% at the interval of 100 ms with electrical stimuli to the 3rd finger, and 20.6% at the interval of 90 ms with a mechanical tap to the Ist interosseous space. Activation of pain receptors induce prepulse inhibition of the blink reflex at a delay corresponding to a slowly conducting pathway. The percentage inhibition is similar to that observed with other somatosensory inputs. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:08:46