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Titolo:
Update on familial cancer syndromes and the skin
Autore:
Tsao, H;
Indirizzi:
Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 Dermatol, Boston, MA 02114 USA
Titolo Testata:
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
fascicolo: 6, volume: 42, anno: 2000,
pagine: 939 - 969
SICI:
0190-9622(200006)42:6<939:UOFCSA>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE ENDOCRINE NEOPLASIA; BASAL-CELL CARCINOMA; PEUTZ-JEGHERS-SYNDROME; TUMOR-SUPPRESSOR GENE; TUBEROUS SCLEROSIS COMPLEX; ROTHMUND-THOMSON-SYNDROME; GERM-LINE MUTATIONS; NONPOLYPOSIS COLORECTAL-CANCER; NEUROFIBROMATOSIS TYPE-1 GENE; OCULAR FUNDUS LESIONS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
302
Recensione:
Indirizzi per estratti:
Indirizzo: Tsao, H Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 , Boston, MA 02114 USA
Citazione:
H. Tsao, "Update on familial cancer syndromes and the skin", J AM ACAD D, 42(6), 2000, pp. 939-969

Abstract

Familial cancer syndromes reflect an inherited predisposition to develop benign and malignant tumors. Clinically the cancers occur at an earlier age and involve multiple foci of tumor formation at multiple sites. In the past10 years, the molecular basis of many of these cancer syndromes have been unraveled with the advent of powerful genetic technologies. Entities which were hypothesized to be related on the basis of clinical features have now been shown to be linked or disparate through genetic analysis. This articlereviews some of the recent advances in the clinical and molecular aspects of familial cancer syndromes that involve the skin.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 22:22:20