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Titolo:
Factors influencing vascular and hepatic enhancement at CT: Experimental study on injection protocol using a canine model
Autore:
Han, JK; Kim, AY; Lee, KY; Seo, JB; Kim, TK; Choi, BI; Lhee, CS; Han, MC;
Indirizzi:
Seoul Natl Univ, Coll Med, Dept Radiol, Seoul, South Korea Seoul Natl Univ Seoul South Korea Med, Dept Radiol, Seoul, South Korea Seoul Natl Univ, Coll Med, Inst Radiat Med, Seoul, South Korea Seoul Natl Univ Seoul South Korea , Inst Radiat Med, Seoul, South Korea
Titolo Testata:
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
fascicolo: 3, volume: 24, anno: 2000,
pagine: 400 - 406
SICI:
0363-8715(200005/06)24:3<400:FIVAHE>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTRAST-MEDIUM INJECTION; HELICAL CT; SPIRAL CT; REDUCTION; VOLUME; LIVER; RATES;
Keywords:
computed tomography; contrast media; liver, neoplasms; animal studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Han, JK Seoul Natl Univ Hosp, Dept Radiol, Chongno Gu, 28 Yongon Dong, Seoul 110744, South Korea Seoul Natl Univ Hosp 28 Yongon Dong Seoul South Korea 110744 orea
Citazione:
J.K. Han et al., "Factors influencing vascular and hepatic enhancement at CT: Experimental study on injection protocol using a canine model", J COMPUT AS, 24(3), 2000, pp. 400-406

Abstract

Purpose: The purpose of this work was to evaluate the effects of contrast medium injection parameters on aortic, portal vein, and hepatic enhancementat spiral CT and to assess optimal injection protocol for hepatic CT. Method: Ten 15 kg dogs underwent single level dynamic CT through the hepatic hilum at 5 s intervals just after the injection of contrast medium for 3min. With use of different volumes (1, 2, and 3 ml/kg), injection rates (0.5, 1, and 2 ml/s), and concentrations (150, 200, and 300 mg/ml), a total of 270 spiral CT scans were performed. In each scan. time-attenuation curvesof aorta, portal vein, and liver were obtained. The degree of maximum contrast enhancement (I-max), time to maximum enhancement (T-max), and time to equilibrium phase (T-eq) for to each injection protocol were analyzed. Results: Alterations in contrast material volume, injection rate, and concentration had significant impact on contrast enhancement of the liver. Withincreasing volume of contrast medium, I-max, T-max, and T-eq of aorta, portal vein, and liver increased (p < 0.005). With increasing rate of injection, on the other hand, I-max of aorta and liver increased (p < 0.05), but T-max and T-eq decreased (p < 0.005). Change of concentration of contrast medium had a significant effect on I-max of vessels (p < 0.05). Conclusion: Maximum contrast enhancement of liver and vessels was influenced mainly by injection volume of contrast medium and the time to peak enhancement by injection rate of contrast medium. Under given amounts of contrast medium, therefore, the strategy of increasing volume by dilution and faster injection might give better I-max values without penalty for the duration of an optimal temporal window (T-max and T-eq).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 13:20:03