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Titolo:
Hemispheric preference in visuospatial processing: A complementary approach with fMRI and lesion studies
Autore:
Ng, VWK; Eslinger, PJ; Williams, SCR; Brammer, MJ; Bullmore, ET; Andrew, CM; Suckling, J; Morris, RG; Benton, AL;
Indirizzi:
Inst Psychiat, Neuroimaging Res Grp, London SE5 8AF, England Inst Psychiat London England SE5 8AF ng Res Grp, London SE5 8AF, England Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Neurol Sect, Hershey,PA 17033 USA Penn State Univ Hershey PA USA 17033 d, Neurol Sect, Hershey,PA 17033 USA Inst Psychiat, Dept Biostat & Comp, London SE5 8AF, England Inst PsychiatLondon England SE5 8AF tat & Comp, London SE5 8AF, England Inst Psychiat, Dept Psychol, London SE5 8AF, England Inst Psychiat London England SE5 8AF pt Psychol, London SE5 8AF, England Univ Iowa, Dept Neurol, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 wa, Dept Neurol, Iowa City, IA 52242 USA
Titolo Testata:
HUMAN BRAIN MAPPING
fascicolo: 2, volume: 10, anno: 2000,
pagine: 80 - 86
SICI:
1065-9471(200006)10:2<80:HPIVPA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMAGE-ANALYSIS; SPECIALIZATION; ACTIVATION; INFERENCE; ATTENTION; JUDGMENT; NETWORK;
Keywords:
fMRI; BOLD; parietal lobe; laterality; wavelet; visuospatial;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Ng, VWK Inst Psychiat, Neuroimaging Res Grp, De Crespigny Pk, Denmark Hill, LondonSE5 8AF, England Inst Psychiat De Crespigny Pk, Denmark Hill London England SE5 8AF
Citazione:
V.W.K. Ng et al., "Hemispheric preference in visuospatial processing: A complementary approach with fMRI and lesion studies", HUM BRAIN M, 10(2), 2000, pp. 80-86

Abstract

Historically, the left cerebral hemisphere has been considered specializedfor language, whereas the right cerebral hemisphere is aligned with spatial processes. However, studies have called into question adherence to this model and suggested that both hemispheres participate in language and spatial cognition. Using functional Magnetic Resonance Imaging (fMRI) and human brain lesion studies, we determined whether these complementary techniques could clarify issues of hemispheric dominance. Using a modified Benton Judgement of Line Orientation (JLO) test, considered a relatively pure spatial processing task, we found robust and significant (p < 0.0005) bilateral superior parietal lobe activation on fMRI in ten right-handed male adult volunteers. This was corroborated by lesion data in a cohort of 17 patients who showed significant JLO impairments after either right or left parietal lobe damage, with right parietal damage associated with somewhat more severe deficit. Detailed wavelet analysis of the fMRI time-series did, however, reveal a more dominant role of the right parietal lobe in "kick-starting" the task. To our knowledge, this is a novel way of using fMRI to address functional hemispheric differences in a cognitive task that is known to have bilateral representation. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 02:45:00