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Titolo:
Exposure of plasma proteins on Dacron and ePTFE vascular graft material ina perfusion model
Autore:
Falkenback, D; Lundberg, F; Ribbe, E; Ljungh, A;
Indirizzi:
Univ Lund, Dept Infect Dis & Med Microbiol, S-22362 Lund, Sweden Univ Lund Lund Sweden S-22362 Dis & Med Microbiol, S-22362 Lund, Sweden
Titolo Testata:
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
fascicolo: 5, volume: 19, anno: 2000,
pagine: 468 - 475
SICI:
1078-5884(200005)19:5<468:EOPPOD>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
COAGULASE-NEGATIVE STAPHYLOCOCCI; BACTERIAL ADHERENCE; POLYMER SURFACES; CLUMPING FACTOR; SOLID-SURFACES; FIBRONECTIN; VITRONECTIN; FIBRINOGEN; AUREUS; ADSORPTION;
Keywords:
vascular graft; ePTFE; Dacron; adhesion; adsorption; plasma proteins;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Ljungh, A Univ Lund, Dept Infect Dis & Med Microbiol, Solvegatan 23, S-22362 Lund, Sweden Univ Lund Solvegatan 23 Lund Sweden S-22362 -22362 Lund, Sweden
Citazione:
D. Falkenback et al., "Exposure of plasma proteins on Dacron and ePTFE vascular graft material ina perfusion model", EUR J VAS E, 19(5), 2000, pp. 468-475

Abstract

Objectives: to compare the exposure of plasma proteins adsorbed onto threevascular graft materials (polytetrafluoroethylene ePTFE and two modifications of polyethyleneterephthalate Dacron). Methods: surface exposure of fibronectin, vitronectin, thrombospondin, antithrombin III, IgG, high molecular-weight kininogen, fibrinogen, albumin and plasminogen was studied by incubation with radiolabelled antibodies in a perfusion model. Perfusion times with human plasma were 1, 4, 24 and 48 hours. Results: all proteins could be detected at 1, 4, 24 and 48 hours after thestart of perfusion. Overall, the least amount of proteins adsorbed onto ePTFE. Conclusions: the low adsorption of proteins onto ePTFE may be one of the reasons for the lower incidence of infections reported with this material.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/21 alle ore 16:15:32