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Titolo:
MtDNA and Y chromosome polymorphisms in Hungary: inferences from the palaeolithic, neolithic and Uralic influences on the modern Hungarian gene pool
Autore:
Semino, O; Passarino, G; Quintana-Murci, L; Liu, AP; Beres, J; Czeizel, A; Santachiara-Benerecetti, AS;
Indirizzi:
Univ Pavia, Dipartimento Genet & Microbiol A Buzzati Traverso, I-27100 Pavia, Italy Univ Pavia Pavia Italy I-27100 A Buzzati Traverso, I-27100 Pavia, Italy Univ Calabria, Dipartimento Biol Cellulare, Arcavacata, Italy Univ Calabria Arcavacata Italy imento Biol Cellulare, Arcavacata, Italy Natl Inst Hyg, Dept Human Genet & Teratol, H-1966 Budapest, Hungary Natl Inst Hyg Budapest Hungary H-1966 Teratol, H-1966 Budapest, Hungary
Titolo Testata:
EUROPEAN JOURNAL OF HUMAN GENETICS
fascicolo: 5, volume: 8, anno: 2000,
pagine: 339 - 346
SICI:
1018-4813(200005)8:5<339:MAYCPI>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MITOCHONDRIAL-DNA ANALYSIS; HUMAN-POPULATIONS; ANALYSIS REVEALS; TANDEM REPEAT; 9-BP DELETION; EUROPE; MICROSATELLITES; HAPLOTYPES; AFFINITIES; MARKERS;
Keywords:
Hungary; Paloc; mtDNA variations; Y chromosome polymorphisms;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
60
Recensione:
Indirizzi per estratti:
Indirizzo: Santachiara-Benerecetti, AS Univ Pavia, Dipartimento Genet & Microbiol A Buzzati Traverso, Via Abbiategrasso 207, I-27100 Pavia, Italy Univ Pavia ViaAbbiategrasso 207 Pavia Italy I-27100
Citazione:
O. Semino et al., "MtDNA and Y chromosome polymorphisms in Hungary: inferences from the palaeolithic, neolithic and Uralic influences on the modern Hungarian gene pool", EUR J HUM G, 8(5), 2000, pp. 339-346

Abstract

Magyars imposed their language on Hungarians but seem not to have affectedtheir genetic structure. To better investigate this point, we analysed some mtDNA and Y chromosome polymorphisms in a sample of the Hungarian Paloc who, for historical reasons, could have retained genetic traces of Magyars more than other groups. In addition, we examined a mixed sample from Budapest. About 100 individuals were tested for the markers defining all the European and Asian mtDNA haplogroups and about 50 individuals for some Y chromosome markers, namely the 12f2 and 49a,f/Taql RFLPs, the YAP insertion, the microsatellites YCAIIa, YCAIIb, DYS19 and the Asian 50f2/C deletion. In the mtDNA analysis only two subjects belonged to the Asian B and M haplogroups. The Y chromosome analyses showed that the Paloc differed from the Budapestsample by the absence of YAP(+) allele and by the DYS19 allele distribution; that the proto-European 49a,f Ht 15 and the neolithic 12f2-8Kb were rather uncommon in both groups; that there is a high prevalence of the 49a,f Ht11 and the YCAII a5-b1; and that the Asian 50f2/C deletion is absent. These results suggest that the influence of Magyars on the Hungarian gene pool has been very low through both females and males and the Hungarian languagecould be an example of cultural dominance. Alternative explanations are discussed. An expansion centred on YAP(-); 49a,f Ht 11 is revealed by the median network based on compound haplotypes. 49a,f Ht 11 could represent either a paleolithic marker of eastern Europe which underwent expansion after the last glacial period, or a marker of the more recent spread of the Yamnaiaculture from southern Ukraine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 20:04:08