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Titolo:
Contrast enhanced power Doppler sonography: Comparison of different administration forms of the ultrasound contrast agent Levovist (R)
Autore:
Kratzer, W; Kachele, V; Merkle, E; Mason, RA; Buchner, M; von Tirpitz, C; Pfeiffer, M;
Indirizzi:
Univ Ulm Klinikum, Innere Med Abt 1, D-89081 Ulm, Germany Univ Ulm Klinikum Ulm Germany D-89081 re Med Abt 1, D-89081 Ulm, Germany Univ Ulm Klinikum, Rontgendiagnost Abt, D-89081 Ulm, Germany Univ Ulm Klinikum Ulm Germany D-89081 diagnost Abt, D-89081 Ulm, Germany Univ Ulm Klinikum, Abt Neurol, D-89081 Ulm, Germany Univ Ulm Klinikum Ulm Germany D-89081 , Abt Neurol, D-89081 Ulm, Germany
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 5, volume: 172, anno: 2000,
pagine: 443 - 448
SICI:
1438-9029(200005)172:5<443:CEPDSC>2.0.ZU;2-N
Fonte:
ISI
Lingua:
GER
Soggetto:
SMALL HEPATOCELLULAR-CARCINOMA; FOCAL NODULAR HYPERPLASIA; LIVER-LESIONS; US; VASCULARIZATION; PATTERNS; TUMORS;
Keywords:
ultrasound, contrast-enhanced Dopplersonography; ultrasound, power-Doppler; ultrasound, contrast media; Levovist; tumor vascularity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Kratzer, W Univ Ulm Klinikum, Innere Med Abt 1, Robert Koch Str 8, D-89081Ulm, Germany Univ Ulm Klinikum Robert Koch Str 8 Ulm Germany D-89081 ermany
Citazione:
W. Kratzer et al., "Contrast enhanced power Doppler sonography: Comparison of different administration forms of the ultrasound contrast agent Levovist (R)", ROFO-F RONT, 172(5), 2000, pp. 443-448

Abstract

Purpose: Objective of the present study was the comparison of various administration forms of the ultrasound contrast medium Levovist(R) with regard to duration and intensity of contrast enhancement in patients with tumors of the liver or pancreas. Patients and Methods: Seven patients with tumors of the liver or pancreas were examined prospectively using power Doppler sonography. Ultrasound contrast enhancement was achieved using Levovist(R) (8 ml, 400 mg/ml) in three different administration forms: 1(st) as a bolus injection through the main channel, 2(nd) through the injection valve of an intravenous cannula, or 3(rd) as a continuous infusion. Semiquantitative evaluation of the degree of contrast enhancement over the course of the examination was conducted by three independent examiners. Results: Levovist(R), administered by continuous infusion, resulted in a significantly longer average period of contrast enhancement (9:43 min (extratumoral), 7:34 min (intratumoral)) than did the same dosage administered as a bolus injection through the main channel (6:01 min (extratumoral), 4:54 min (intratumoral), p = 0.0156 (extratumoral); p = 0.0313 (intratumoral), but contrast intensity was decreased. Bolus injection through the injection valve of the i.v. cannula was associated with decreased duration and intensity of contrast enhancement compared with injection through the main channel. Conclusion: Compared with bolus injection, the continuous infusion of Levovist(R) resulted in a significant prolongation of the duration but in a decreased intensity of contrast enhancement. Administration of Levovist(R) through the injection valve does not result in optimal contrast enhancement and is therefore not recommended.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 12:57:13