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Titolo:
ENDOSCOPIC ENDONASAL TRANSSPHENOIDAL SURGERY - EXPERIENCE WITH 50 PATIENTS
Autore:
JHO HD; CARRAU RL;
Indirizzi:
PRESBYTERIAN UNIV HOSP,DEPT NEUROL SURG,SUITE B-400,200 LOTHROP ST PITTSBURGH PA 15213 UNIV PITTSBURGH,SCH MED,DEPT NEUROL SURG PITTSBURGH PA 15261 UNIV PITTSBURGH,SCH MED,DEPT OTOLARYNGOL PITTSBURGH PA 15261
Titolo Testata:
Journal of neurosurgery
fascicolo: 1, volume: 87, anno: 1997,
pagine: 44 - 51
SICI:
0022-3085(1997)87:1<44:EETS-E>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
PITUITARY-TUMOR SURGERY; MANAGEMENT;
Keywords:
CHORDOMA; CRANIOPHARYNGIOMA; CUSHINGS DISEASE; ENDOSCOPY; PITUITARY TUMOR; PROLACTINOMA; TRANSSPHENOIDAL APPROACH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
H.D. Jho e R.L. Carrau, "ENDOSCOPIC ENDONASAL TRANSSPHENOIDAL SURGERY - EXPERIENCE WITH 50 PATIENTS", Journal of neurosurgery, 87(1), 1997, pp. 44-51

Abstract

An endoscope was used in transsphenoidal surgery and eventually replaced the operating microscope as the tool for visualization. This studyfocuses on 50 patients (28 females and 22 males) with a median age of38 years (range 14-88 years). Initially, four patients underwent operation via a sublabial-transseptal approach using a rigid endoscope in conjunction with an operating microscope. The 38 subsequent operationswere performed through a nostril using only rigid endoscopes. Forty-four patients had pituitary adenomas and six had various other lesions. Thirteen patients had microadenomas, 16 had intrasellar macroadenomas, nine had macroadenomas with suprasellar extension and six had invasive macroadenomas involving the cavernous sinus. When patients had recurrent pituitary adenomas and 25 had hormone-secreting adenomas (eight patients with Gushing's disease and 17 patients with prolactinomas). Among the right patients with Cushing's disease, seven had resolution of hypercortisolism clinically and chemically. Of the 17 patients with prolactinomas. 10 improved clinically with normal serum prolactin levels, four improved clinically with elevated serum prolactin levels, andthree had residual tumors in the cavernous sinus. Among the 19 patients with nonsecreting adenomas, 16 underwent total resection and three subtotal resection leaving residual tumor in the cavernous sinus. Postoperatively, ail patients who had undergone endonasal endoscopic surgery had unobstructed nasal airways with minimal discomfort. More than half of the patients required only an overnight hospitalization.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 15:20:32