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Titolo:
Prevalence and associated factors for fatty liver in apparent healthy adult men
Autore:
Pares, A; Tresserras, R; Nunez, I; Cerralbo, M; Plana, P; Pujol, FJ; Massip, J; Caballeria, L; Bru, C; Caballeria, J; Vidal, J; Salleras, L; Rodes, J;
Indirizzi:
Univ Barcelona, Hosp Clin, Unidad Hepatol, E-08036 Barcelona, Spain Univ Barcelona Barcelona Spain E-08036 Hepatol, E-08036 Barcelona, Spain Univ Barcelona, Hosp Clin, Unidades Alcohol, E-08036 Barcelona, Spain UnivBarcelona Barcelona Spain E-08036 Alcohol, E-08036 Barcelona, Spain Univ Barcelona, Hosp Clin, Ctr Diagnost Imatge, E-08036 Barcelona, Spain Univ Barcelona Barcelona Spain E-08036 Imatge, E-08036 Barcelona, Spain Generalitat Catalunya, Direccio Gen Salut Publ, Dept Sanitat & Seguretat Social, Catalunya, Spain Generalitat Catalunya Catalunya Spain eguretat Social, Catalunya, Spain Serv Med Empresa Aigues Barcelona, Barcelona, Spain Serv Med Empresa Aigues Barcelona Barcelona Spain ona, Barcelona, Spain Univ Barcelona, Unidad Bioestadist, Dept Salud Publ & Legislac Sanitaria, E-08007 Barcelona, Spain Univ Barcelona Barcelona Spain E-08007 nitaria, E-08007 Barcelona, Spain
Titolo Testata:
MEDICINA CLINICA
fascicolo: 15, volume: 114, anno: 2000,
pagine: 561 - 565
SICI:
0025-7753(20000422)114:15<561:PAAFFF>2.0.ZU;2-J
Fonte:
ISI
Lingua:
SPA
Soggetto:
NONALCOHOLIC STEATOHEPATITIS; ALCOHOLIC HEPATITIS; NATURAL-HISTORY; CIRRHOSIS; FIBROSIS; DISEASE; OBESITY; RISK; INFILTRATION; INJURY;
Keywords:
alcoholism; diabetes; obesity; dyslipemia; hepatic ultrasonography; fatty liver;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Pares, A Univ Barcelona, Hosp Clin, Unidad Hepatol, Villarroel 170, E-08036 Barcelona, Spain Univ Barcelona Villarroel 170 Barcelona Spain E-08036 ona, Spain
Citazione:
A. Pares et al., "Prevalence and associated factors for fatty liver in apparent healthy adult men", MED CLIN, 114(15), 2000, pp. 561-565

Abstract

BACKGROUND: Alcohol intake in one of the factors associated with fatty liver, although its contribution as well as other fators have not been completely established. Therefore the aim of this study was to assess the prevalence and associated factors for fatty liver diagnosed by ultrasonography. SUBJECTS AND METHODS: 1,801 presumably healthy male workers (age range 18-60 years). A complete physical and laboratory investigations, including HBsAg and anti-HCV antibodies, a detailed interview on alcohol intake, and an abdominal ultrasound examination were performed in all cases. Diagnosis of fatty liver was based on defined ultrasonographic criteria. RESULTS: Eighty eight cases were excluded because of the HBsAg or anti-HCVpositivity or incomplete ultrasonography. Among the remaining 1,713 cases,236 (13.8%; 12.2-15.4) had fatty liver. Logistic regression analysis disclosed age (RR: 1.04; Cl 95%; 1.03-1.05), ethanol intake > 40 g/d (2.19; 1.81-2.65), gamma-glutamyl-transferase > 40 U/l (3.51; 2.95-4.18), body mass index > 30 (3.87; 3.22-4.66) and glycemia > 120 mg/dl (2.69; 1,85-3.90) as the risk factors for fatty liver. Fatty liver was present in 8.8% of cases who did not have obesity, diabetes or hypercholesterolemia. When the subjectswith obesity, hyperglycemia or hypercholesterolemia were excluded, regression analysis confirmed age, ethanol intake and gamma-glutamyl-transferase as independent factors associated with fatty liver. CONCLUSIONS: Age, alcohol intake, obesity, and increased serum levels of glucose, cholesterol and gammaglutamyl transferase are the main factors associated with fatty liver in presumably healthy adult men.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 15:38:50