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Titolo:
Auditory brainstem responses in Rett syndrome: Effects of hyperventilation, seizures, and tympanometric variables
Autore:
Pillion, JP; Rawool, VW; Naidu, S;
Indirizzi:
Kennedy Krieger Inst, Dept Audiol, Baltimore, MD 21205 USA Kennedy KriegerInst Baltimore MD USA 21205 diol, Baltimore, MD 21205 USA Bloomsburg Univ Penn, Dept Speech Pathol & Audiol, Bloomsburg, PA 17815 USA Bloomsburg Univ Penn Bloomsburg PA USA 17815 ol, Bloomsburg, PA 17815 USA
Titolo Testata:
AUDIOLOGY
fascicolo: 2, volume: 39, anno: 2000,
pagine: 80 - 87
SICI:
0020-6091(200003/04)39:2<80:ABRIRS>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVOKED-POTENTIALS; AUTISM;
Keywords:
auditory brainstem response; hyperventilation; middle ear; Rett syndrome; seizures; tympanometry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Pillion, JP Kennedy Krieger Inst, Dept Audiol, 707 N Broadway, Baltimore, MD 21205 USA Kennedy Krieger Inst 707 N Broadway Baltimore MD USA 21205 USA
Citazione:
J.P. Pillion et al., "Auditory brainstem responses in Rett syndrome: Effects of hyperventilation, seizures, and tympanometric variables", AUDIOLOGY, 39(2), 2000, pp. 80-87

Abstract

This study examined the effects of tympanometric variables, stage of disease, hyperventilation, and seizures on the auditory brainstem response (ABR)in Rett syndrome (RS). Thirty-four female children with RS ranging in age from 2 years, 3 months to 15 years, 7 months participated in the study. ABRs and tympanograms were recorded from all of the subjects. When the ABR peaks were identifiable, interpeak latency intervals (IPLIs) for I-III, III-V,and I-V were computed for each waveform. The peaks (I, III, and V) and IPLIs were characterized as abnormal if either the peaks were absent or the latencies were greater than 2 SD from the normative data (obtained on female children). Analyses revealed significant prolongation of wave I latencies in Rett children with abnormal tympanograms. ABR wave III latencies were significantly affected by the presence of seizures and hyperventilation. The Pearson chi-square statistic revealed significant differences in the rate ofwave III and V abnormalities due to the presence and degree of hyperventilation and the presence of seizures. Wave I abnormalities were also observedin the presence of normal middle ear function, suggesting the presence of sensorineural hearing impairment in some RS children. Clinical implicationsof these findings are discussed.

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Documento generato il 22/01/20 alle ore 12:31:32