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Titolo:
Diagnosis of cutaneous B-cell lymphomas
Autore:
Flaig, MJ; Sander, CA;
Indirizzi:
Univ Munich, Klin & Poliklin Dermatol & Allergol, D-80337 Munich, Germany Univ Munich Munich Germany D-80337 l & Allergol, D-80337 Munich, Germany
Titolo Testata:
PATHOLOGE
fascicolo: 2, volume: 21, anno: 2000,
pagine: 190 - 196
SICI:
0172-8113(200003)21:2<190:DOCBL>2.0.ZU;2-X
Fonte:
ISI
Lingua:
GER
Soggetto:
EUROPEAN-AMERICAN CLASSIFICATION; BCL-2 PROTEIN EXPRESSION; CLINICOPATHOLOGICAL ANALYSIS; NEOPLASMS REAL; ZONE LYMPHOMA; FOLLOW-UP; SKIN; ANGIOENDOTHELIOMATOSIS; PLASMACYTOMA; LEUKEMIA;
Keywords:
cutaneous lymphoma; cutaneous B-cell lymphoma; WHO-classification;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Sander, CA Univ Munich, Klin & Poliklin Dermatol & Allergol, Frauenlobstr 9-11, D-80337 Munich, Germany Univ Munich Frauenlobstr 9-11 Munich GermanyD-80337 , Germany
Citazione:
M.J. Flaig e C.A. Sander, "Diagnosis of cutaneous B-cell lymphomas", PATHOLOGE, 21(2), 2000, pp. 190-196

Abstract

Skin is the second most common site of extranodal lymphoma. The significance of cutaneous B-cell lymphomas has been underestimated due to the lack ofmonoclonal antibodies and molecular genetics in former years. Cutaneous B-cell lymphomas represent a heterogenous group of entities which show variation in histology, immunophenotype and in prognosis. The most common entities presenting in skin are follicular lymphomas, marginal zone B-cell lymphomas, and diffuse large B-cell lymphomas. The majority of primary cutaneous B-cell lymphomas have an excellent prognosis. Whereas in B-cell lymphomas with secondary spread to the skin the clinical course is dependant on the prognosis of the primary lymphoma. It is evident that primary cutaneous lymphomas are distinct from nodal lymphomas and not extranodal manifestations of their lymph-node-based counterparts. In the current review the morphologic spectrum of cutaneous B-cell lymphomas comprising primary and secondary cutaneous B-cell lymphomas is discussed according to the WHO classification sheme.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 10:10:51