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Titolo:
Vitamin A deficiency in children aged 6 to 24 months in Sao Paulo State, Brazil
Autore:
Ferraz, IS; Daneluzzi, JC; Vannucchi, H;
Indirizzi:
Univ Sao Paulo, Dept Child Care & Pediat, Fac Med Ribeirao Preto, BR-14049900 Ribeirao Preto, Brazil Univ Sao Paulo Ribeirao Preto Brazil BR-14049900 BCibeirao Preto, Brazil Univ Sao Paulo, Fac Med Ribeirao Preto, Div Clin Nutrol, Dept Internal Med, BR-05508 Sao Paulo, Brazil Univ Sao Paulo Sao Paulo Brazil BR-05508 Med, BR-05508 Sao Paulo, Brazil
Titolo Testata:
NUTRITION RESEARCH
fascicolo: 6, volume: 20, anno: 2000,
pagine: 757 - 768
SICI:
0271-5317(200006)20:6<757:VADICA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
RETINOL-BINDING PROTEIN; A-DEFICIENCY; RISK-FACTORS; BANGLADESHI CHILDREN; ZINC SUPPLEMENTATION; BETA-CAROTENE; MILD VITAMIN; BIRTH-WEIGHT; XEROPHTHALMIA; SERUM;
Keywords:
vitamin A deficiency; xerophthalmia; breast-feeding; child; zinc;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Ferraz, IS Univ Sao Paulo, Dept Child Care & Pediat, Fac Med Ribeirao Preto, Av Bandeirantes 3900, BR-14049900 Ribeirao Preto, Brazil Univ Sao Paulo Av Bandeirantes 3900 Ribeirao Preto Brazil BR-14049900 BC
Citazione:
I.S. Ferraz et al., "Vitamin A deficiency in children aged 6 to 24 months in Sao Paulo State, Brazil", NUTR RES, 20(6), 2000, pp. 757-768

Abstract

Vitamin A deficiency (VAD), mainly the subclinical form, is endemic in several areas of the Brazilian Northeast. However, studies concerning its prevalence and etiology (risk factors) in urban areas of Sao Paulo State are lacking. The objective of the present study was to identify VAD and the risk factors among children attending a Child Care outpatient clinic in RibeiraoPreto city, Sb Paulo State, Brazil. A total of 103 children aged 6 to 24 months without any diarrhea or fever illness were selected from a pediatric outpatient clinic. A careful clinical history and physical examination provided information about breast-feeding, parental education, family income, family size, birth weight and anthropometric data. The children also underwent ophthalmologic examination to check for signs of xerophthalmia and were submitted to blood tests in order to determine hemoglobin and serum iron, zinc and retinol levels. Serum retinol levels pound 0.70 mu mol/l are considered to be deficient by the World Health Organization. Retinol levels, determined by high performance liquid chromatography (HPLC), were pound? 0.70 mu?mol/l in 22 children (21.4%). No child had xerophthalmia. The overall mean serum zinc level was 108.9 mu g% (2SD +/- 43.1 mu g%) and the values for children with and without VAD were 105.1 mu g% (2SD +/- 44.1 mu g%) and 110.0 mu g% (2SD r 43.2 mu g%) respectively, with no child presenting serum zinc levels below the normal range. None of them showed a <? -2 Z score for height/age or weight/height compared to reference values. No Significant differences were observed between children with or without VAD concerning parental education, family income, family size and hemoglobin, or serum iron and zinc levels, but low birth weight (<? 2,500 g) was more frequent among children with VAD. Moreover, children without VAD were breast-fed for a significantly longer time than children with VAD (p<0.05). Children with VAD presented a history of low birth weight more frequently than children without VAD and breast-feeding was protective against VAD. This study showed that VAD is an important problem in children attending a Child Care outpatient clinic and that studies are needed in order to identify it and plan actions to combat it, mainly by encouraging breast-feeding practices. (C) 2000 Elsevier Science.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 01:08:58