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Titolo:
Diagnostic evaluation of the breast using PET: Optimization of data acquisition and postprocessing
Autore:
Brix, G; Henze, M; Doll, J; Lucht, R; Zaers, J; Trojan, H; Knopp, MV; Haberkorn, U;
Indirizzi:
Bundesamt Strahlenschutz, Inst Strahlenhyg, Abt Med Strahlenhyg, D-85764 Neuherberg, Germany Bundesamt Strahlenschutz Neuherberg Germany D-85764 Neuherberg, Germany Univ Klinikum Heidelberg, Abt Nukl Med, Heidelberg, Germany Univ Klinikum Heidelberg Heidelberg Germany kl Med, Heidelberg, Germany Deutsch Krebsforschungszentrum, Forsch Schwerpunkt Radiol Diagnost & Therapie, D-6900 Heidelberg, Germany Deutsch Krebsforschungszentrum HeidelbergGermany D-6900 elberg, Germany
Titolo Testata:
NUKLEARMEDIZIN
fascicolo: 3, volume: 39, anno: 2000,
pagine: 62 - 66
Fonte:
ISI
Lingua:
GER
Soggetto:
ITERATIVE IMAGE-RECONSTRUCTION; POSITRON-EMISSION-TOMOGRAPHY; PERFORMANCE EVALUATION; SCATTER CORRECTION; 3D; OVERRELAXATION; MAMMOGRAPHY; SUBSETS; CANCER;
Keywords:
positron emission tomography; breast cancer; 3D data acquisition; dose reduction; image fusion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Brix, G Bundesamt Strahlenschutz, Inst Strahlenhyg, Abt Med Strahlenhyg, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany Bundesamt StrahlenschutzIngolstadter Landstr 1 Neuherberg Germany D-85764
Citazione:
G. Brix et al., "Diagnostic evaluation of the breast using PET: Optimization of data acquisition and postprocessing", NUKLEARMED, 39(3), 2000, pp. 62-66

Abstract

Purpose: Development and evaluation of on optimized protocol for PET examinations of the female breast with 2-F-18-fluoro-2-deoxyglucose (F-18-FDG). Methods: All PET measurements were performed with a whole-body PET system (ECAT EXACT HR+). in order to examine the women with the breasts freely pendant, a special extension far the patient table mode of carbon layer composite was designed. After data acquisition in the 3D modus, emission data weresorted into 2D sinograms using the Fourier rebinning algorithm and reconstructed by means of an ultra-fast iterative 2D algorithm (HOSP). The reconstructed emission scans were superimposed onto the corresponding transmissionimages. The protocol presented was evaluated in examinations on 6 women with breast lesions after the administration of 150-220 MBq F-18-FDG. From two adjacent bed positions, emission and transmission data were acquired overperiods of 20 min and 10 min, respectively. For comparison dynamic magnetic resonance (MR) image series were acquired with a whole-body MR system (MAGNETOM SP 4000) using a double-breast coil. Results and Conclusion: Using the designed extension of the patient table, it was possible to examine corpulent women despite the limited patient port of the PET system in the proneposition with the breasts freely pendant. Alongside a reduction in motion artifacts, this positioning also offers the possibility of making a direct comparison between PET and MR images. Despite the fact that the amount of F-18-FDG applied to the patient was markedly reduced, the combination of 3D data acquisition and iterative image reconstruction resulted in excellent quality of the emission scans. By superpositioning of iteratively reconstructed emission and transmission scans, anatomical localization of breast lesions visualized on the emission scans could be improved. The postprocessing of the PET data described was completed in 60 min, this meaning that the presented concept con readily be employed in clinical practice.

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Documento generato il 09/04/20 alle ore 20:14:31