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Titolo:
Comparison of Tl-201 SPET and treadmill exercise testing in patients with Kawasaki disease
Autore:
Jan, SL; Hwang, B; Fu, YC; Lee, PC; Kao, CH; Liu, RS; Chi, CS;
Indirizzi:
Taichung Vet Gen Hosp, Dept Pediat, Taichung, Taiwan Taichung Vet Gen Hosp Taichung Taiwan sp, Dept Pediat, Taichung, Taiwan
Titolo Testata:
NUCLEAR MEDICINE COMMUNICATIONS
fascicolo: 5, volume: 21, anno: 2000,
pagine: 431 - 435
SICI:
0143-3636(200005)21:5<431:COTSAT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; LYMPH-NODE SYNDROME; MYOCARDIAL-INFARCTION; NONINVASIVE ASSESSMENT; FOLLOW-UP; CHILDREN; SCINTIGRAPHY; DIPYRIDAMOLE; STENOSES; ISCHEMIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Hwang, B Taipei Vet Gen Hosp, Dept Pediat, 201,Sect 2,Shih Pai Rd, Taipei,Taiwan Taipei Vet Gen Hosp 201,Sect 2,Shih Pai Rd Taipei Taiwan Taiwan
Citazione:
S.L. Jan et al., "Comparison of Tl-201 SPET and treadmill exercise testing in patients with Kawasaki disease", NUCL MED C, 21(5), 2000, pp. 431-435

Abstract

About 4% of children with Kawasaki disease ultimately develop ischaemic heart disease. Therefore, the early detection, non-invasive monitoring and long-term follow-up of myocardial ischaemia are essential. We compared the sensitivity and specificity of Tl-201 Single photon emission tomography (SPET) and treadmill exercise in the detection of myocardial ischaemia in 23 patients (19 boys, 4 girls) with Kawasaki disease. They were divided into two groups according to the results of coronary angiography. Group I consisted of 11 patients with coronary abnormalities; Group II consisted of 12 patients with no coronary abnormalities. The sensitivity, specificity, false-positive and false-negative rates for detecting coronary arterial lesions were 72.7% (8/11), 58.3% (7/12), 38.5% (5/13) and 30% (3/10) for Tl-201 SPET, and 45.5% (5/11), 100% (12/12), 0% (0/5) and 33.3% (6/18) for treadmill exercise, respectively. We conclude that Tl-201 SPET is more sensitive than treadmill exercise for the detection of coronary arterial abnormalities, but that the specificity of treadmill exercise is better than that of Tl-201 scintigraphy. Coronary artery lesions detected by coronary angiography have good concordance of ischaemic areas with perfusion defects detected by Tl-201 SPET. When ischaemic findings on Tl-201 SPET and/or positive treadmill exercise testing are noted, coronary angiography is strongly indicated to detect possible stenotic lesions in the coronary arteries. ((C) 2000 Lippincott Williams & Wilkins).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 10:38:56