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Titolo:
The Frontal Behavioral Inventory in the differential diagnosis of frontotemporal dementia
Autore:
Kertesz, A; Nadkarni, N; Davidson, W; Thomas, AW;
Indirizzi:
St Josephs Hlth Ctr, Dept Cognit Neurol, London, ON, Canada St Josephs Hlth Ctr London ON Canada t Cognit Neurol, London, ON, Canada
Titolo Testata:
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
fascicolo: 4, volume: 6, anno: 2000,
pagine: 460 - 468
SICI:
1355-6177(200005)6:4<460:TFBIIT>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY PROGRESSIVE APHASIA; MULTI-INFARCT DEMENTIA; ALZHEIMERS-DISEASE; VASCULAR DEMENTIA; PICKS-DISEASE; CRITERIA; FEATURES; SYMPTOMS;
Keywords:
frontotemporal dementia; Pick's disease; Frontal Behavioral Inventory;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Kertesz, A Univ Western Ontario, St Josephs Hlth Ctr, Dept Neurol, 268 Grosvenor St, London, ON N6A 4V2, Canada Univ Western Ontario 268 Grosvenor StLondon ON Canada N6A 4V2
Citazione:
A. Kertesz et al., "The Frontal Behavioral Inventory in the differential diagnosis of frontotemporal dementia", J INT NEURO, 6(4), 2000, pp. 460-468

Abstract

A personality and behavioral disorder is an important and defining featureof frontal lobe dementia (FLD) or frontotemporal degeneration (FTD). The diagnosis usually depends on the progressive development of various behavioral symptoms rather than a set of neuropsychological measures. Quantification of the personality-behavior disorder is important for standardizing the diagnosis. An inventory was constructed to capture the major positive and negative behaviors and personality change, and it was administered prospectively to caregivers of 108 patients in a cognitive neurology clinic, at the time of first diagnostic assessment. The prevalence and extent of behavioralabnormality was quantitated in the clinic population of FLD, vascular dementia (VaD), Alzheimer's disease (AD), primary progressive aphasia (PPA), and depressive disorder (DD) patients. The mean scores of FLD patients were significantly above all other groups. Scores in VaD were also higher than inAD, PPA, and DD. Interrater reliability (Cohen's kappa of .90) and item consistency (a Cronbach alpha of .89) were both high. Perseveration indifference inattention, inappropriateness, and loss of insight rated highest in FLD, significantly different from all other groups. Apathy, aspontaneity, inflexibility, disorganization, impulsivity, personal neglect, and poor judgement were also significantly higher in FLD. Discriminant function correctly classified 92.7% versus all other patients (NON-FLD) in the study. A total of 18.8% of VaD patients were misclassified as FLD. Indifference, alien hand, and inappropriateness were the highest discriminant functions. Perseveration and verbal apraxia were important discriminatory items for FLD and PPA, respectively. The FBI is a standardized behavioral inventory useful to diagnose FLD, to differentiate it from other dementias, and to quantify the behavior disorder.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/06/20 alle ore 14:14:16