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Titolo:
Attention in HIV-infected children: Results from the Hemophilia Growth andDevelopment Study
Autore:
Watkins, JM; Cool, VA; Usner, D; Stehbens, JA; Nichols, S; Loveland, KA; Bordeaux, JD; Donfield, S; Asarnow, RF; Nuechterlein, KH;
Indirizzi:
Childrens Hosp Orange Cty, Dept Hlth Psychol & Neuropsychol, Orange, CA 92668 USA Childrens Hosp Orange Cty Orange CA USA 92668 ychol, Orange, CA 92668 USA Univ Iowa, Coll Med, Dept Pediat, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 ed, Dept Pediat, Iowa City, IA 52242 USA Oregon State Univ, Dept Stat, Corvallis, OR 97331 USA Oregon State Univ Corvallis OR USA 97331 pt Stat, Corvallis, OR 97331 USA Univ Calif San Diego, Dept Pediat, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 Pediat, La Jolla, CA 92093 USA Univ Texas, Sch Med, Dept Psychiat & Behav Sci, Houston, TX USA Univ Texas Houston TX USA ed, Dept Psychiat & Behav Sci, Houston, TX USA Rice Univ, Houston, TX 77251 USA Rice Univ Houston TX USA 77251Rice Univ, Houston, TX 77251 USA Rho Inc, Chapel Hill, NC USA Rho Inc Chapel Hill NC USARho Inc, Chapel Hill, NC USA Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA Univ Calif Los Angeles Los Angeles CA USA 90024 Los Angeles, CA 90024 USA
Titolo Testata:
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
fascicolo: 4, volume: 6, anno: 2000,
pagine: 443 - 454
SICI:
1355-6177(200005)6:4<443:AIHCRF>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUSTAINED ATTENTION; SIGNAL-DETECTION; CHILDHOOD; ADHD; ENCEPHALOPATHY; HYPERACTIVITY; BEHAVIOR; SPEED; TIME;
Keywords:
hemophilia; HIV; pediatric AIDS; attention;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Watkins, JM Childrens Hosp Orange Cty, Dept Hlth Psychol & Neuropsychol, 455 S Main St, Orange, CA 92668 USA Childrens Hosp Orange Cty 455 S Main St Orange CA USA 92668 SA
Citazione:
J.M. Watkins et al., "Attention in HIV-infected children: Results from the Hemophilia Growth andDevelopment Study", J INT NEURO, 6(4), 2000, pp. 443-454

Abstract

Attentional functioning was examined in three groups of 7- to 19-year-old male participants with hemophilia: (1) HIV seronegative controls (HIV-, N =66), (2) HIV seropositive participants with CD4+ lymphocyte counts greaterthan or equal to 200 (HIV+ CD4+ greater than or equal to 200, N = 79), and(3) severely immune suppressed HIV seropositive participants (HIVS CD4+ <200, N = 28). Two measures sensitive to attention deficits were used: the Continuous Performance Test (CPT) and the Span of Apprehension (Span). On theCPT, there was a decrement in attention in both HIV+ groups, as indexed byan increase in false alarm rate from Block 1 to Block 3, that was not present in the HIV- group. The longer the HIV+ children were required to sustain attention to the CPT, the more they responded to the incorrect stimulus. This effect decreased as age increased. Span percent correct and latency tocorrect were associated with the presence of a premorbid history of intracerebral hemorrhage, but were not sensitive to HIV status or degree of immune suppression in the HIV+ children, suggesting morbidity related to hemophilia. The remaining CPT and Span variables-hit rate, sensitivity, latency, percent correct, and latency to correct-showed the expected associations with age, but none showed conclusive associations with HIV status or immune suppression in the HIV+ participants.

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Documento generato il 25/01/20 alle ore 19:30:19