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Titolo:
Candidaemia in special care nurseries: Comparison of Albicans and Parapsilosis infection
Autore:
Huang, YC; Lin, TY; Lien, RI; Chou, YH; Kuo, CY; Yang, PH; Hsieh, WS;
Indirizzi:
Chang Gung Univ, Div Pediat Infect Dis, Chang Gung Childrens Hosp, Tao Yuan, Taiwan Chang Gung Univ Tao Yuan Taiwan g Gung Childrens Hosp, Tao Yuan, Taiwan Chang Gung Univ, Div Neonatol, Chang Gung Childrens Hosp, Tao Yuan, TaiwanChang Gung Univ Tao Yuan Taiwan g Gung Childrens Hosp, Tao Yuan, Taiwan
Titolo Testata:
JOURNAL OF INFECTION
fascicolo: 2, volume: 40, anno: 2000,
pagine: 171 - 175
SICI:
0163-4453(200003)40:2<171:CISCNC>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
BIRTH-WEIGHT INFANTS; NEONATAL CANDIDIASIS; FUNGAL COLONIZATION; AMPHOTERICIN-B; FLUCONAZOLE; OUTBREAK; FUNGEMIA; ASSOCIATION; CANDIDEMIA; DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Huang, YC Chang Gung Univ, Div Pediat Infect Dis, Chang Gung Childrens Hosp, 5 Fu Shin St, Tao Yuan, Taiwan Chang Gung Univ 5 Fu Shin St Tao Yuan Taiwan Tao Yuan, Taiwan
Citazione:
Y.C. Huang et al., "Candidaemia in special care nurseries: Comparison of Albicans and Parapsilosis infection", J INFECTION, 40(2), 2000, pp. 171-175

Abstract

Objectives: Candidaemia caused by Candida parapsilosis (CP) is being increasingly reported among infants in neonatal intensive care units (NICU). To assess relative severity clinical manifestations of candidaemia caused by C. albicans (CA) and CP in a NICU were compared. Methods: Between January 1994 and July 1997, episodes of candidaemia occurring among infants hospitalized in the NICU were identified in a children'shospital. The demographic characteristics, associated risk factors, clinical manifestations and outcome of the infants with CP fungaemia were collected and compared with those of the infants with CA fungaemia. Results: Twenty-four episodes caused by CA and 22 episodes caused by CP were included in this study, No significant differences were found between the two groups for gestational age, birth weight, male gender. post-natal ageat onset of candidaemia, frequency of antecedent neonatal events, prior duration of antibiotic therapy and hyperalimentation, as well as presence of central vt:nous catheter (CVC), Infants with CA fungaemia were significantly more likely than those with CP fungaemia to present with hypoxaemia, bradycardia and respiratory distress requiring intubation, and have a longer prior duration of indwelling CVC and a higher dissemination rate. The eradication rate of candidaemia and overall case fatality race were comparable in both groups, but CP fungaemia did not appear to cause acute lethal events. Conclusions: The presenting, signs of CP fungaemia are relatively not so severe, but CP fungaemia, which is relatively difficult to eradicate, increases the morbidity and mortality of the infants. (C) 2000 The British Infection Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:39:43