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Titolo:
Update on vancomycin resistance
Autore:
Perichon, B; Courvalin, P;
Indirizzi:
Inst Pasteur, Unite Agents Antibacteriens, F-75724 Paris 15, France Inst Pasteur Paris France 15 ts Antibacteriens, F-75724 Paris 15, France
Titolo Testata:
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
fascicolo: 4, volume: 54, anno: 2000,
pagine: 250 - 254
SICI:
1368-5031(200005)54:4<250:UOVR>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENTEROCOCCUS-FAECIUM BM4147; DEPSIPEPTIDE PEPTIDOGLYCAN PRECURSORS; ALANYL-D-ALANINE; GLYCOPEPTIDE RESISTANCE; GALLINARUM BM4174; FAECALIS; GENE; VANB; CONFERS; ENZYMES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Courvalin, P Inst Pasteur, Unite Agents Antibacteriens, 25 Rue Dr Roux, F-75724 Paris 15, France Inst Pasteur 25 Rue Dr Roux Paris France 15 Paris 15, France
Citazione:
B. Perichon e P. Courvalin, "Update on vancomycin resistance", INT J CL PR, 54(4), 2000, pp. 250-254

Abstract

Enterococci can be responsible for severe infections such as endocarditis,meningitis and septicaemia and are one of the most important causes of nosocomial infections. Resistance in enterococci concerns many classes of antibiotics including, since 1986, glycopeptides. These antibiotics act by blocking cell wall formation, and resistance is due to synthesis of modified peptidoglycan precursors. Resistance can be acquired or intrinsic and strainsmay be resistant to vancomycin and teicoplanin, or to vancomycin only. Five types of glycopeptide resistance and their biochemical mechanisms have been described. Furthermore, strains that are dependent on vancomycin for growth have been isolated from clinical samples. Data suggest that resistance could originate in glycopeptide-producing organisms or in enterococcal species intrinsically resistant to these antibiotics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 05:53:04