Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Analysis of synaptic quantal depolarizations in smooth muscle using the wavelet transform
Autore:
Venkateswarlu, PVK; Desai, UB; Manchanda, R;
Indirizzi:
Indian Inst Technol, Sch Biomed Engn, Bombay 400076, Maharashtra, India Indian Inst Technol Bombay Maharashtra India 400076 6, Maharashtra, India Indian Inst Technol, Dept Elect Engn, Bombay 400076, Maharashtra, India Indian Inst Technol Bombay Maharashtra India 400076 6, Maharashtra, India
Titolo Testata:
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
fascicolo: 6, volume: 47, anno: 2000,
pagine: 701 - 708
SICI:
0018-9294(200006)47:6<701:AOSQDI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
PIG VAS-DEFERENS; GUINEA-PIG; JUNCTION POTENTIALS; VARICOSITIES; TRANSMITTER; SECRETION;
Keywords:
neuromuscular transmission; signal processing; smooth muscle; synaptic potentials; wavelet transform;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Engineering, Computing & Technology
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Manchanda, R Indian Inst Technol, Sch Biomed Engn, Bombay 400076, Maharashtra, India Indian Inst Technol Bombay Maharashtra India 400076 a, India
Citazione:
P.V.K. Venkateswarlu et al., "Analysis of synaptic quantal depolarizations in smooth muscle using the wavelet transform", IEEE BIOMED, 47(6), 2000, pp. 701-708

Abstract

The time-frequency characteristics of synaptic potentials contain valuableinformation about the process of neurotransmission between nerves and their target organs. For example, at the synapse between autonomic nerves and smooth muscle, two central issues of neurophysiology, i,e., I) the probability of ntiurotransmitter release and 2) the quantal behavior of transmissioncan be deduced from analysis of the rising phases of evoked excitatory junction potentials (eEJP's) recorded from smooth muscle. eEJP rising phases are marked by prominent inflexions, which reflect these Features of neuronalactivity. Since these inflexions contain time-varying frequency information, we have applied recent techniques of time-frequency analysis based upon wavelet transforms to eEJP's recorded from the guinea-pig vas deferens ill vitro. We find that these techniques allow accurate and convenient characterization of neuronal release sites, and that their probability of release falls between 0.001-0,004, We have also analyzed eEJP's recorded in the presence of the chemical 1-heptanol, which reveals quantal depolarizations. These results have helped clarify the nature of the quantal depolarizations that underly eEJP's. The present method offers significant advantages over those previously employed for these tasks, and holds promise as a novel approach to the analysis of synaptic potentials.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 09:16:41